Effect of Polysaccharide Iron Complex Capsules and Sustained Release Tablets of Ferrous Succinate on Iron Deficiency Anemia in Pregnant Women in the Second Trimester
Objective To investigate the curative effect of polysaccharide iron complex capsules and sustained release tablets of ferrous succinate on iron deficiency anemia in pregnant women in the second trimester.Methods A total of 112 pregnant women with iron deficiency anemia in the second trimester treated in Gaomi People's Hospital from Feb-ruary 2023 to February 2024 were conveniently selected as the study objects.According to different treatment meth-ods,they were divided into polysaccharide iron complex group and ferrous succinate group,with 56 cases each.The therapeutic effect,incidence of adverse reactions,blood indexes and pregnancy outcome of the two groups were com-pared.Results The total effective rate of treatment polysaccharide iron complex group was 96.43%,compared with the ferrous succinate group(91.07% ),and the difference was not statistically significant(χ2=0.609,P>0.05).The inci-dence of adverse reactions in polysaccharide iron complex group was 5.36%,which was significantly lower than that in ferrous succinate group(17.86% ),and the difference was statistically significant(χ2=4.264,P<0.05).After treatment,the hematocrit,hemoglobin,erythrocyte count and serum ferritin of polysaccharide iron complex group were higher than those of ferrous succinate group,and the differences were statistically significant(all P<0.05).There was no sta-tistically significant difference in adverse pregnancy outcomes(preterm birth,fetal distress,postpartum hemorrhage and low birth weight)between the two groups(all P>0.05).Conclusion Polysaccharide iron complex capsules and sus-tained release tablets of ferrous succinate can both obtain good curative effect in the treatment of iron deficiency ane-mia in the second trimester and prevent adverse pregnancy outcomes,while sugar iron complex has the advantages of improving reticulocyte and iron metabolism and less adverse reactions.
Iron deficiency anemiaPolysaccharide iron complexFerrous succinateAdverse reactionsPregnancy outcome
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