首页|血清D-二聚体及心肌酶谱对急性肺血栓栓塞的诊断价值分析

血清D-二聚体及心肌酶谱对急性肺血栓栓塞的诊断价值分析

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目的 分析血清D-二聚体及心肌酶谱在急性肺血栓栓塞诊断中的价值.方法 简单随机选取2018年2月—2023年11月苏州大学附属第二医院收治的50例急性肺血栓栓塞患者纳入观察组,选择同期的50例健康体检者纳入对照组.对比两组的天门冬氨酸氨基转移酶(Aspartate Transaminase,AST)、乳酸脱氢酶(Lactate Dehydrogenase,LDH)、肌酸激酶(Creatine Kinase,CK)、肌酸激酶同工酶(Creatine Kinase Isoenzyme-MB,CK-MB)水平及血清中D-二聚体的水平和诊断效果.结果 观察组的AST、LDH、CK、CK-MB水平及血清中D-二聚体的水平高于对照组,差异有统计学意义(P均<0.05).AST、LDH、CK、CK-MB联合D-二聚体诊断急性肺血栓栓塞的特异度为90.00%、灵敏度为90.00%、准确度为90.00%,kappa值为0.8.结论 心肌酶谱联合血清中D-二聚体对于急性肺血栓栓塞的诊断价值较高,可在临床诊断工作中加以应用.
Diagnostic Value of Serum D-dimer and Myocardial Enzyme Profile in Acute Pulmonary Thromboembolism
Objective To analyze the value of serum D-dimer and myocardial enzyme profile in the diagnosis of acute pulmonary thromboembolism.Methods 50 patients with acute pulmonary thromboembolism admitted to the Second Af-filiated Hospital of Soochow University from February 2018 to November 2023 were simple randomly selected in the observation group,and 50 healthy subjects from the same period were included in the control group.The levels of as-partate transaminase(AST),lactate dehydrogenase(LDH),creatine kinase(CK),creatine kinase isoenzyme-MB(CK-MB),serum D-dimer and diagnostic effect were compared between the two groups.Results The levels of AST,LDH,CK,CK-MB and serum D-dimer in observation group were higher than those in control group,and the differences were statistically significant(all P<0.05).The specificity,sensitivity and accuracy of AST,LDH,CK,CK-MB com-bined with D-dimer in the diagnosis of acute pulmonary thromboembolism were 90.00%,90.00%,90.00%,and kappa was 0.8.Conclusion Myocardial enzyme profile combine with D-dimer in serum have high diagnostic value for acute pulmonary thromboembolism and can be used in clinical diagnosis.

D-dimerMyocardial enzyme profileAcute pulmonary thromboembolismClinical diagnosis

邓安雨、张鹏、刘慧

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苏州大学附属第二医院检验科,江苏苏州 215000

D-二聚体 心肌酶谱 急性肺血栓栓塞 临床诊断

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(15)