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新生儿肺炎治疗中氨溴索联合布地奈德雾化的应用效果分析

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目的 探究氨溴索与布地奈德联合治疗新生儿肺炎的效果.方法 方便选取2021年1月—2023年12月南平市第二医院收治的121例患有新生儿肺炎患儿为研究对象,依据随机数表法分为两组,对照组(n=60)采用氨溴索治疗;观察组(n=61)在对照组用药基础上应用布地奈德雾化治疗.比较两组患者疗效、炎症因子水平、免疫功能水平和症状消失时间.结果 观察组临床疗效(98.36%)高于对照组(86.67%),差异有统计学意义(x2=6.008,P<0.05).治疗前,两组患者炎症因子水平比较,差异无统计学意义(P>0.05),治疗后,观察组炎症因子水平低于对照组,差异有统计学意义(P<0.05).治疗前,两组患者免疫功能比较,差异无统计学意义(P>0.05),治疗后,观察组免疫功能高于对照组,差异有统计学意义(P<0.05).治疗后,观察组症状消失时间短于对照组,差异有统计学意义(P<0.05).结论 氨溴索、布地奈德联合应用在新生儿肺炎治疗中,能促进改善炎症因子,增强免疫功能,加快症状消失的速度,具有较高应用价值.
Analysis of the Effectiveness of Ambroxol Combined with Budesonide Nebulization Application in the Treatment of Neonatal Pneumonia
Objective To investigate the effect of the combination of ambroxol and budesonide in the treatment of neo-natal pneumonia.Methods 121 cases of pneumonia neonates admitted to Nanping Second Hospital from January 2021 to December 2023 were conveniently selected as the study objects,and were divided into two groups according to the method of random number table,the control group(n=60)was treated with ambroxol,and the observation group(n=61)was treated by budesonide nebulization based on the medication used in the control group.Compare the efficacy,in-flammatory factor level,immune function level and symptom disappearance time of the two groups.Results The clini-cal efficacy of the observation group(98.36%)was higher than that of the control group(86.67%),and the difference was statistically significant(x2=6.008,P<0.05).Before treatment,the inflammatory factor level of patients in the two groups were compared,and the difference was not statistically significant(P>0.05),after treatment,the inflammatory factor level of the observation group was lower than that of the control group,and the difference was statistically sig-nificant(P<0.05).Before treatment,the immune function of the two groups of patients was compared,and the differ-ence was not statistically significant(P>0.05),after treatment,the immune function of the observation group was higher than the control group,and the difference was statistically significant(P<0.05).After treatment,the disappear-ance time of symptoms in the observation group was shorter than that in the control group,and the difference was sta-tistically significant(P<0.05).Conclusion The combined application of ambroxol and budesonide in the treatment of neonatal pneumonia can promote the improvement of inflammatory factors,enhance the immune function,and acceler-ate the speed of symptom disappearance,which has high application value.

NeonatePneumoniaAmbroxolBudesonideNebulization therapy

魏辉兰、魏荣乐、吴国平

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南平市第二医院儿科,福建南平 354200

新生儿 肺炎 氨溴索 布地奈德 雾化治疗

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(15)