性激素替代联合常规保健对妇女围绝经期综合征的治疗效果评估
Evaluation of the Therapeutic Effect of Sex Hormone Replacement Com-bined with Conventional Health Care on Perimenopausal Syndrome in Women
刘颖 1胡枚 1刘霞1
作者信息
- 1. 福州市仓山区妇幼保健院,福建福州 350008
- 折叠
摘要
目的 探讨常规保健治疗的同时施以性激素替代治疗的价值.方法 随机选取2023年1-12月于福州市仓山区妇幼保健院就诊并诊断为围绝经期综合征的60例患者为研究对象,使用随机抽签法分成对照组与观察组,每组30例.对照组施以常规保健治疗,观察组采用常规保健治疗联合性激素替代疗法.对比两组临床效果、激素水平和症状评分.结果 观察组治疗总有效率为93.33%,高于对照组的73.33%,差异有统计学意义(x2=4.320,P=0.037).相比对照组,观察组治疗后雌二醇相对更高,黄体生成素与促卵泡激素则较低,差异有统计学意义(P均<0.05).观察组治疗后症状评分低于对照组,差异有统计学意义(P<0.05).结论 围绝经期综合征患者在实施常规保健的基础上指导性激素替代疗法的疗效显著,可使患者激素水平得到良好的调节,促进减轻症状.
Abstract
Objective To explore the value of administering sex hormone replacement therapy along with conventional health care treatment.Methods Sixty patients diagnosed with perimenopausal syndrome in Fuzhou Cangshan District Maternal and Child Health Hospital from January to December 2023 were randomly selected as the study objects and divided into a control group and an observation group,with 30 patients in each group by the random draw method.The control group was treated with conventional health care therapy,and the observation group was treated with conven-tional health care therapy combined with sex hormone replacement therapy.The clinical effects,hormone levels and symptom scores of the two groups were compared.Results The total effective rate of treatment in the observation group was 93.33%,which was higher than that of 73.33%in the control group,and the difference was statistically significant(x2=4.320,P=0.037).Compared with the control group,the observation group had relatively higher estradiol and lower luteinizing hormone and follicle-stimulating hormone after treatment,and the differences were statistically significant(all P<0.05).Symptom score dimensions was lower in the observation group than in the control group after treatment,and the difference was statistically significant(P<0.05).Conclusion The efficacy of directing sex hormone replace-ment therapy in patients with perimenopausal syndrome based on the implementation of conventional health care is re-markable,which can lead to a good regulation of hormone levels and promote the reduction of symptoms.
关键词
围绝经期综合征/常规保健/性激素替代/临床症状/激素水平Key words
Perimenopausal syndrome/Conventional health care/Sex hormone replacement/Clinical symptoms/Hormone level引用本文复制引用
出版年
2024
NETL
NSTL
万方数据