首页|氯吡格雷联合依达拉奉治疗脑梗死的疗效分析

氯吡格雷联合依达拉奉治疗脑梗死的疗效分析

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目的 分析氯吡格雷联合依达拉奉治疗脑梗死的疗效.方法 随机选择单县中心医院于2022年1月—2023年9月收治的150例脑梗死患者为研究对象,抽签法分组,对照组75例,使用氯吡格雷治疗,干预组75例,开展氯吡格雷联合依达拉奉联合治疗,对比两组的临床疗效.结果 干预组治疗有效率(94.67%)高于对照组(80.00%),差异有统计学意义(x2=7.292,P<0.05).治疗后,干预组的日常生活能力、神经功能评分优于对照组,差异有统计学意义(P均<0.05).治疗后,干预组的神经元特异性烯醇化酶、半胱氨酸天冬氨酸蛋白酶、同型半胱氨酸及炎性因子均低于对照组,差异有统计学意义(P均<0.05).治疗后,干预组的生活质量评分高于对照组,差异有统计学意义(P<0.05).结论 氯吡格雷联合依达拉奉治疗脑梗死,效果良好,有临床研究意义.
Analysis of the Efficacy of Clopidogrel Combined with Edaravone in the Treatment of Cerebral Infarction
Objective To analyze the efficacy of clopidogrel combined with edaravone in the treatment of cerebral in-farction.Methods 150 cases of cerebral infarction patients admitted to Shanxian Central Hospital from January 2022 to September 2023 were randomly selected as research subjects,grouped by lottery method,75 cases in the control group were treated with clopidogrel,75 cases in the intervention group were treated with clopidogrel combined with edaravone,and the clinical efficacy of the two groups was compared.Results The effective rate of the intervention group(94.67%)was higher than that of the control group(80.00%),and the difference was statistically significant(x2=7.292,P<0.05).After treatment,the daily living ability and neurological function scores of the intervention group were better than those of the control group,and the differences were statistically significant(both P<0.05).After treatment,the neuron-specific enolase,cysteine aspartate protease,homocysteine and inflammatory factor of the intervention group were lower than those of the control group,and the differences were statistically significant(all P<0.05).After treatment,the quality of life score of the intervention group was higher than that of the control group,and the differ-ence was statistically significant(P<0.05).Conclusion Clopidogrel combined with edaravone in the treatment of cere-bral infarction,the effect is good,and has clinical value significance.

Cerebral infarctionEdaravoneClopidogrelCombined treatment

孙冠军、戚远

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单县中心医院神经内科,山东菏泽 274300

脑梗死 依达拉奉 氯吡格雷 联合治疗

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(15)