首页|托伐普坦片联合托拉塞米片治疗对老年心力衰竭患者心功能的影响分析

托伐普坦片联合托拉塞米片治疗对老年心力衰竭患者心功能的影响分析

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目的 探讨托伐普坦片与托拉塞米片联合治疗对老年心力衰竭患者心功能的影响.方法 方便选取厦门市中医院于2021年9月—2023年11月收治96例老年心力衰竭患者作为研究对象,采取随机数表法分为两组,各48例.对照组患者接受托拉塞米片治疗,研究组予托伐普坦片联合托拉塞米片治疗,比较两组患者治疗前后的心功能指标、临床相关指标,治疗后的临床疗效及不良反应发生率.结果 治疗后,研究组患者心功能指标水平与临床相关指标均优于对照组,差异有统计学意义(P均<0.05);研究组患者的临床治疗总有效率为97.92%高于对照组的81.25%,差异有统计学意义(x2=7.144,P<0.05);研究组不良反应总发生率低于对照组,差异有统计学意义(P<0.05).结论 托伐普坦片联合托拉塞米片治疗老年心力衰竭患者,其心功能和临床相关指标显著改善,且临床治疗效果显著,安全性较高.
Analysis of the Effect of Tolvaptan Tablets Combined with Torasemide Tablets Treatment on Cardiac Function in Elderly Patients with Heart Failure
Objective To explore the effect of combined treatment of tolvaptan tablets and torasemide tablets on car-diac function of elderly patients with heart failure.Methods A total of 96 elderly patients with heart failure admitted to Xiamen Hospital of Traditional Chinese Medicine from September 2021 to November 2023 were conveniently se-lected as the study subjects,and were divided into two groups of 48 patients each by random number table method.Pa-tients in the control group were treated with torasemide tablets,and the study group was treated with tolvaptan tablets combined with torasemide tablets.Compare the cardiac function indexes and clinical related indexes before and after the treatment of the two groups of patients,and compare the clinical efficiency and the incidence of adverse reactions after the treatment of the two groups of patients.Results After treatment,the level of cardiac function indexes and clinical related indexes of the patients in the study group were better than those of the control group,and the differ-ences were statistically significant(both P<0.05).The total clinical treatment efficiency of patients in the study group was 97.92%,which was higher than 81.25%in the control group,and the difference was statistically significant(x2=7.144,P<0.05).The total incidence of adverse reactions in the study group was lower than that in the control group,and the difference was statistically significant(P<0.05).Conclusion Tolvaptan tablets combined with torasemide tab-lets in the treatment of elderly patients with heart failure,its cardiac function and clinical related indexes significantly improved,and the clinical therapeutic effect is significant,and the safety is high.

Tolvaptan tabletsTorasemide tabletsElderly heart failureCardiac functionBrain natriuretic peptideEffective rate

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厦门市中医院老年科,福建厦门 361009

托伐普坦片 托拉塞米片 老年心力衰竭 心功能 脑钠肽 有效率

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(15)
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