Study on the Value of Small Bone Flap Craniotomy Hematoma Removal Combined with Bone Flap Repositioning in the Treatment of Cerebral Hemorrhage Cerebral Hernia
Objective To explore the clinical value of small bone flap craniotomy hematoma removal combined with bone flap repositioning in the treatment of cerebral hemorrhage cerebral hernia.Methods A total of 80 patients with hypertensive basal ganglia hemorrhage resulting in cerebral hernia formation admitted to Jiaozhou Hospital of Dong-fang Hospital Affiliated to Tongji University from February 2022 to September 2023 were prospective randomly se-lected as the study objects.They were divided into two groups according to the method of random number table method,each with 40 cases.In the control group,large bone flap craniotomy hematoma removal combined with de-bridement decompression surgery was performed,and in the observation group,small bone flap craniotomy hematoma removal combined with cranial bone repair was performed.The postoperative levels of vascular endothelial growth fac-tor(VEGF),basic fibroblast growth factor(bFGF),endothelin-1(ET-1),and nitric oxide(NO)were compared between the two groups,and the changes of inflammatory factors and intracranial pressure between the two groups were counted after surgery.Results Postoperative VEGF and bFGF levels in the observation group were(80.2±9.3)pg/mg and(42.9±6.3)pg/mg,respectively,which were higher than those in the control group,and the differences were statis-tically significant(t=9.915,16.997,both P<0.05).The level of ET-1 in the observation group was lower than that in the control group,and the level of NO was higher than that in the control group,the differences were statistically sig-nificant(both P<0.05).high-sensitivity-C-reactive protein and tumor necrosis factor-α in the observation group were lower than those in the control group,and the differences were statistically significant(both P<0.05).The intra-cranial pressure of the observation group was lower than that of the control group,and the cerebral perfusion pressure was significantly higher than that of the control group,and the differences were statistically significant(both P<0.05).Conclusion For hypertensive basal ganglia cerebral hemorrhage complicating cerebral herniation,small bone flap cra-niotomy hematoma removal combined with bone flap repositioning can effectively improve the postoperative vascular endothelial growth function,reduce the inflammatory response,and lower intracranial pressure.
Small bone flap craniotomy hematoma removalBone flap repositioningCerebral hemorrhageCerebral hernia
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