Clinical Efficacy Analysis of Percutaneous Transhepatic Gallbladder Drainage Combined with Laparoscopic Cholecystectomy in the Treatment of Acute Severe Cholecystitis
Objective To investigate the clinical efficacy of percutaneous transhepatic gallbladder drainage and laparo-scopic cholecystectomy in patients with acute severe cholecystitis.Methods A total of 90 patients with acute severe cholecystitis admitted to Chizhou People's Hospital of Anhui Province from February 2020 to December 2023 were randomly selected as the research objects.According to the random number table method,they were divided into con-trol group and observation group,with 45 cases in each group.The control group was treated with laparoscopic chole-cystectomy,and the observation group was combined with percutaneous transhepatic gallbladder puncture and drain-age surgery.The operation condition,inflammatory reaction and complication rate of the two groups were analyzed.Results The operation time,postoperative anal exhaust time,hospitalization time and intraoperative blood loss in the observation group were better than those in the control group,and the differences were statistically significant(all P<0.05).The postoperative C-reactive protein was(58.13±15.65)mg/L and procalcitonin was(1.77±0.35)ng/mL in the observation group,which were lower than(79.98±21.35)mg/L,(2.23±0.42)ng/mL in the control group,the differences were statistically significant(t=5.537,5.644,both P<0.05);the incidence of complications(common bile duct injury,biliary fistula,infection,bile duct injury)in the observation group was 2.22%,which was lower than 22.22%in the control group,and the difference was statistically significant(χ2=8.389,P<0.05).Conclusion The use of percutaneous transhepatic gallbladder puncture drainage combined with laparoscopic cholecystectomy can improve clinical symp-toms,reduce complications,and achieve better surgical outcomes.
Acute severe cholecystitisLaparoscopic cholecystectomyPercutaneous transhepatic gallbladder puncture and drainage surgeryInflammatory responseComplications
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