中外医疗2024,Vol.43Issue(17) :9-12.DOI:10.16662/j.cnki.1674-0742.2024.17.009

舒更葡糖钠应用于老年患者深肌松腹腔镜手术的效果分析

Analysis of the Effect of Sugammadex Sodium Application in Deep Muscle Relaxation Laparoscopic Surgery in Elderly Patients

徐海龙 吴靓 王远征 衡垒
中外医疗2024,Vol.43Issue(17) :9-12.DOI:10.16662/j.cnki.1674-0742.2024.17.009

舒更葡糖钠应用于老年患者深肌松腹腔镜手术的效果分析

Analysis of the Effect of Sugammadex Sodium Application in Deep Muscle Relaxation Laparoscopic Surgery in Elderly Patients

徐海龙 1吴靓 2王远征 1衡垒3
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作者信息

  • 1. 徐州市肿瘤医院麻醉科,江苏 徐州 221000
  • 2. 徐州市第一人民医院麻醉科,江苏 徐州 221000
  • 3. 徐州新健康老年病医院麻醉科,江苏 徐州 221000
  • 折叠

摘要

目的 分析舒更葡糖钠应用于老年患者深肌松腹腔镜手术的效果.方法 方便选择徐州市肿瘤医院于2023年1-10月收治的82例行腹腔镜手术的老年患者为研究对象,以随机数表法划分为两组,各41例.观察组行舒更葡糖钠拮抗肌松,对照组行新斯的明+阿托品拮抗肌松.对比两组肌松恢复指标、肌松残余情况及并发症.结果 观察组拔管时间、麻醉恢复室停留时间、肌肉恢复指数和TOF恢复至0.9的时间均优于对照组,差异有统计学意义(t=9.383、10.830、11.110、13.181,P均<0.05).用肌松拮抗药5、15 min时,观察组肌松残余率分别为12.20%、0,低于对照组的41.46%、26.83%,差异有统计学意义(χ2=8.945、12.704,P均<0.05).观察组并发症总发生率低于对照组,差异有统计学意义(P<0.05).结论 予以老年患者深肌松腹腔镜手术舒更葡糖钠拮抗肌松,可缩短患者拔管和麻醉恢复室停留时间,肌松残余率较低,并发症较少.

Abstract

Objective To analyze the effect of sugammadex sodium applied to deep muscle relaxation laparoscopic sur-gery in elderly patients.Methods Eighty-two elderly patients admitted to Xuzhou Cancer Hospital for laparoscopic surgery from January to October 2023 were conveniently selected as the study subjects,and were divided into two groups of 41 cases each by random number table method.In the observation group,sugammadex sodium was used to antagonize muscle relaxation,and in the control group,neostigmine+atropine was used to antagonize muscle relax-ation.The two groups were compared in terms of muscle relaxation recovery indexes,muscle relaxation residual condi-tion and complications.Results The observation group's extubation time,anesthesia recovery room stay time,muscle recovery index and TOF recovery to 0.9 were better than that of the control group,the differences were statistically sig-nificant(t=9.383,10.830,11.110,13.181,all P<0.05).At 5 and 15 min with muscarinic antagonist,the residual rate of muscle relaxation in the observation group was 12.20%and 0,respectively,which were lower than that in the con-trol group,which were 41.46%and 26.83%,the differences were statistically significant(χ2=8.945,12.704,both P<0.05).The total complication rate of the observation group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Antagonizing muscle relaxation with deep muscle relaxation laparo-scopic surgery with sugammadex sodium in elderly patients can shorten the time of patients'extubation and anesthesia recovery room stay,with lower residual rate of muscle relaxation and fewer complications.

关键词

腹腔镜手术/舒更葡糖钠/肌松残余/并发症

Key words

Laparoscopic surgery/Sugammadex sodium/Muscle relaxation residuals/Complications

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基金项目

徐州市科技重点研发计划(农业与社会发展)(KC19148)

2023年度江苏大学医教协同创新基金(一般项目)(JDYY2023048)

出版年

2024
中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
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