首页|慢性阻塞性肺疾病患者行特布他林联合布地奈德治疗的价值分析

慢性阻塞性肺疾病患者行特布他林联合布地奈德治疗的价值分析

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目的 分析慢性阻塞性肺疾病(Chronic Obstructive Pulmonary Disease,COPD)患者行特布他林联合布地奈德的治疗的价值.方法 回顾性选取临沂市中医医院于2022年2月—2023年12月收治的95例COPD患者的临床资料,按治疗方式分为对照组(n=45)与观察组(n=50),对照组行沙丁胺醇治疗,观察组行特布他林联合布地奈德治疗,对比两组临床疗效、肺功能指标、症状评分及不良反应发生情况.结果 观察组治疗总有效率为96.00%,高于对照组的82.22%,差异有统计学意义(χ2=4.774,P<0.05).治疗前,两组肺功能指标、症状评分对比,差异无统计学意义(P均>0.05);治疗后,观察组各项肺功能指标均高于对照组,各项症状评分均低于对照组,差异有统计学意义(P均<0.05).两组不良反应发生率对比,差异无统计学意义(P>0.05).结论 COPD以特布他林和布地奈德进行联合治疗有效率更高,对患者肺功能及病症的改善更为显著,且不良反应少.
Analysis of the Value of Treatment with Terbutaline Combined with Budesonide in Patients with Chronic Obstructive Pulmonary Disease
Objective To analyze the value of treatment with terbutaline combined with budesonide in patients with chronic obstructive pulmonary disease(COPD).Methods The clinical data of 95 cases COPD patients admitted to Linyi Hospital of Traditional Chinese Medicine from February 2022 to December 2023 were retrospectively selected and divided into a control group(n=45)and an observation group(n=50)according to the treatment modality.The con-trol group was treated with salbutamol,and the observation group was treated with terbutaline combined with budesonide,comparing the clinical efficacy,pulmonary function indexes,symptom scores and the occurrence of ad-verse reactions between the two groups.Results The total effective rate of treatment in the observation group was 96.00%,which was higher than of the control group(82.22%),and the difference was statistically significant(χ2=4.774,P<0.05).Before treatment,the two groups'pulmonary function indexes and symptom scores were compared,and the difference was not statistically significant(P>0.05);after treatment,all lung function indexes of the observa-tion group were higher than those of the control group,and all symptom scores were lower than those of the control group,and the differences were statistically significant(both P<0.05).There was no significant difference in the inci-dence of abverse reactions between the two groups(P>0.05).Conclusion Combined treatment with terbutaline and budesonide is more effective in COPD,improves lung function and disease more significantly,and has fewer adverse reactions.

Chronic obstructive pulmonary diseaseTerbutalineBudesonideLung functionSymptom reliefSafety

杨珊珊、闫飞、胡浩原

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临沂市中医医院呼吸(肺病)科,山东 临沂 276000

费县妇幼保健院公共卫生科,山东 临沂 273400

慢性阻塞性肺疾病 特布他林 布地奈德 肺功能 症状缓解 安全性

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(17)
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