Comparative Analysis of the Effect of Ciprofol and Propofol in Painless Gastroscopy in Elderly Patients
Objective Exploring the effectiveness of using cyclophenol and propofol during painless gastroscopy in el-derly patients.Methods 104 elderly patients who underwent painless gastroscopy in Tai'an Central Hospital Affili-ated to Qingdao University from July 2022 to July 2023 were conveniently selected as the study subjects,They was divided into propofol group(n=52)and cyclofol group(n=52),Two groups of anesthesia index(induction,insertion,examination,awake,directional force recovery,chamber time,and drug dose),and hemodynamic indicators at differ-ent time points[heart rate(HR),mean arterial pressure(MAP)and saturation of peripheral oxygen SpO2)],the inci-dence of adverse reactions.Results There was no statistically difference in induction time,insertion time,examination time and orientation recovery time between the two groups(all P>0.05).Compared with the propofol group,the awake time[(2.68±0.57)min]and the time of leaving the room[(6.37±0.87)min]in the propofol group were shorter,and the dose of the drug[(45.85±3.67)mg]was less,the differences were statistically significant(t=4.029,6.769,56.047,all P<0.05);There was no statistically significant difference in heart rate between the two groups at different time points(all P>0.05),the mean arterial pressure of the two groups decreased at before examination(T1)and immediate end of examination(T2),and increased at make fulness(T3),there was no statistically significant difference in mean arterial pressure between the two groups at different time points(all P>0.05).The incidence of adverse reactions in the cyclo-pol group was lower than that in the propofol group,the difference was statistically significant(P<0.05).Conclusion Both propofol and cyclopol have good anesthesia effects in painless gastroscopy,and anesthesia satisfaction is high.However,cyclopol has a smaller impact on saturation of peripheral oxygen during the examination process,with fewer adverse reactions and better safety compared to propofol.
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