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药物分娩镇痛对新生儿高胆红素血症的影响分析

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目的 探讨分析药物分娩镇痛对新生儿高胆红素血症的影响.方法 随机选取2022年12月—2023年7月海宁市妇幼保健院出生的、自然分娩的200例新生儿作为研究对象,根据母亲分娩时采用镇痛方式的不同,分为研究组(n=100,药物分娩镇痛新生儿)和对照组(n=100,无药物分娩镇痛自然分娩新生儿).评价两组新生儿出生后的第1~5天的经皮胆红素指数(Transcutaneous Bilirubinometry,TcB),同时统计其高胆红素血症发生率和并发症发生率.结果 研究组新生儿出生第1天、第2天的TcB[(4.90±0.79)、(8.30±1.34)]高于对照组[(4.67±0.83)、(7.53±1.41)],差异有统计学意义(t=2.007、3.958,P均<0.05).研究组与对照组新生儿出生第3~5天的TcB、高胆红素血症发生率及并发症总发生率对比,差异无统计学意义(P均>0.05).结论 药物分娩镇痛与无药物分娩镇痛的高胆红素血症发生率及并发症发生率的效果相当,但是药物分娩镇痛可以改善新生儿出生后前两天的经皮胆红素指数.
The Effect of Medication Delivery Analgesia on Neonatal Hyperbilirubine-mia
Objective To explore and analyze the effect of drug delivery analgesia on neonatal hyperbilirubinemia.Methods A total of 200 neonates born naturally in Haining Maternal and Child Health Hospital from December 2022 to July 2023 were randomly selected as the research objects.According to the different analgesia methods used by mothers during delivery,they were divided into study group(n=100,neonates with drug labor analgesia)and control group(n=100,neonates with natural delivery without drug labor analgesia).The transcutaneous bilirubinometry(TcB)of the two groups of newborns on the 1st to 5th day after birth was evaluated,and the incidence of hyperbiliru-binemia and complications were counted.Results TcB on the 1st and 2nd day of birth in the study group[(4.90±0.79),(8.30±1.34)]were higher than that in the control group[(4.67±0.83),(7.53±1.41)],and the differences were statistically significant(t=2.007,3.958,both P<0.05).There were no significant differences in the TcB on the 3rd to 5th day of birth,the incidence of hyperbilirubinemia and complications between the study group and the control group(all P>0.05).Conclusion The effect of medication delivery analgesia on the incidence of hyperbilirubinemia and complications is comparable to that of non medication delivery analgesia,but medication delivery analgesia can improve the transcutaneous bilirubin index of newborns in the first two days.

Drug delivery analgesiaNeonatal hyperbilirubinemiaTranscutaneous bilirubinometrySerum total bilirubin

沈雪娟、沈吕烨、俞成维

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海宁市妇幼保健院儿科,浙江 海宁 314400

浙江省妇产疾病临床医学研究中心儿科,浙江 海宁 314400

药物分娩镇痛 新生儿高胆红素血症 经皮胆红素指数 血清总胆红素

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(18)