目的 探究重症监护室(Intensive Care Unit,ICU)脑出血术后应用亚低温治疗的临床效果.方法 方便选择2020年1月—2023年12月福建医科大学附属三明市第一医院脑出血术后患者152例为研究对象,依据奇偶数法分为两组,各76例.对照组术后予以常规治疗、研究组术后予以常规治疗+亚低温治疗.比较两组治疗效果、并发症、神经功能、炎症因子、血清指标、活动能力.结果 研究组治疗有效率为97.37%,高于对照组的86.84%,差异有统计学意义(χ2=5.790,P=0.016).研究组并发症总发生率为3.95%,对照组为2.63%,两组比较,差异无统计学意义(P>0.05).治疗后,研究组神经功能优于对照组,差异有统计学意义(P<0.05).治疗后,研究组C反应蛋白、白细胞介素-6水平均低于对照组,差异有统计学意义(P均<0.05).治疗后,研究组血管升压素及内皮素均低于对照组,差异有统计学意义(P均<0.05).治疗后,研究组上肢、下肢活动能力均优于对照组,差异有统计学意义(P均<0.05).结论 亚低温治疗在ICU脑出血术后治疗中应用效果显著.
Clinical Effect of Mild Hypothermia in Patients with Cerebral Hemor-rhage After Operation
Objective To explore the clinical effect of mild hypothermia treatment after intensive care unit(ICU)cere-bral hemorrhage surgery.Methods A total of 152 patients with cerebral hemorrhage after operation in the Sanming First Hospital Affiliated to Fujian Medical University from January 2020 to December 2023 were selected as the study objects,and were divided into two groups according to odd and even number method,with 76 cases in each group.The control group was given conventional treatment and the study group was given conventional treatment+mild hypother-mia.The therapeutic effect,complications,neurological function,inflammatory factors,serum indicators and activity ability of the two groups were compared.Results The effective rate of the study group was 97.37%,higher than that of the control group(86.84%),the difference was statistically significant(χ2=5.790,P=0.016).The total complication rate of the study group was 3.95%,while in the control group was 2.63%,and there was no significant difference be-tween the two group.After treatment,the neurological function of the study group was better than that of the control group,and the difference was statistically significant(P<0.05).After treatment,the levels of C-reactive protein and in-terleukin-6 in the study group were lower than those in the control group,and the differences were statistically signifi-cant(both P<0.05).After treatment,vasopressin and endothelin in the study group were lower than those in the control group,and the differences were statistically significant(both P<0.05).After treatment,the activity ability of upper and lower limbs of the study group were better than those of the control group,and the differences were statistically signifi-cant(both P<0.05).Conclusion The application effect of mild hypothermia treatment in the treatment of ICU cerebral hemorrhage after surgery is significant.
Cerebral hemorrhageIntensive care unitMild hypothermia treatmentNeurological functionActivity ability
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