Study on the Effect of Different Concentrations of Ropivacaine in Surgical Anesthesia
Objective To analyze the application effect of different concentrations of ropivacaine in surgical anesthe-sia.Methods A total of 126 patients who underwent knee arthroplasty in Shanxian Central Hospital from May 2022 to November 2023 were selected as the research objects.According to different concentrations of ropivacaine,they were divided into study group(0.20%ropivacaine)and control group(0.25%ropivacaine),with 63 cases in each group.The pain scores after anesthesia,the changes of patients'signs and stress indicators during anesthesia treatment were com-pared between the two groups.Results The pain scores of the study group at different time periods(1 h,2 h,4 h,6 h)were(1.18±0.05)points,(2.34±0.08)points,(2.47±0.19)points,and(3.15±0.48)points,respectively,which were lower than control group's(1.24±0.04)points,(2.42±0.12)points,(2.68±0.24)points,(3.32±0.42)points,the differ-ences were statistically significant(t=7.437,4.402,5.445,2.115,all P<0.05).Before anesthesia,there was no statisti-cally significant difference in blood pressure and heart rate between the two groups(both P>0.05).Immediately after anesthesia and at the end of operation,the diastolic blood pressure,systolic blood pressure and heart rate in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Imme-diately after anesthesia and at the end of operation,the stress indexes in the study group was better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of ropivacaine anesthetic drug with 0.20%concentration can reduce the pain score,effectively improve the final anesthetic effect,ensure the level of patients'signs and indicators,reduce stress indicators,ensure the smooth progress of surgical treatment,and achieve the final treatment purpose,which has clinical reference significance.