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不同浓度的罗哌卡因在手术麻醉中的应用效果研究

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目的 分析不同浓度罗哌卡因在手术麻醉中的应用效果.方法 选取2022年5月—2023年11月于单县中心医院实施膝关节置换术的126例患者为研究对象,根据麻醉药物不同浓度的罗哌卡因分为研究组(0.20%罗哌卡因)与对照组(0.25%罗哌卡因),各63例.比较两组麻醉实施后的疼痛评分、麻醉治疗期间患者体征变化情况、应激指标情况.结果 研究组不同时间段(1、2、4、6 h)疼痛评分分别为(1.18±0.05)分、(2.34±0.08)分、(2.47±0.19)分、(3.15±0.48)分,均低于对照组的(1.24±0.04)分、(2.42±0.12)分、(2.68±0.24)分、(3.32±0.42)分,差异有统计学意义(t=7.437、4.402、5.445、2.115,P均<0.05).麻醉前,两组患者的血压和心率比较差异无统计学意义(P均>0.05),麻醉即刻、术毕,研究组舒张压、收缩压、心率均低于对照组,差异有统计学意义(P均<0.05).麻醉即刻、术毕,研究组应激指标优于对照组,差异有统计学意义(P<0.05).结论 采用0.20%浓度的罗哌卡因麻醉药物,能够降低疼痛评分,可有效提高最终的麻醉效果,保障患者的体征指标水平,降低应激指标,可保障手术治疗的顺利进行,实现最终治疗目的.
Study on the Effect of Different Concentrations of Ropivacaine in Surgical Anesthesia
Objective To analyze the application effect of different concentrations of ropivacaine in surgical anesthe-sia.Methods A total of 126 patients who underwent knee arthroplasty in Shanxian Central Hospital from May 2022 to November 2023 were selected as the research objects.According to different concentrations of ropivacaine,they were divided into study group(0.20%ropivacaine)and control group(0.25%ropivacaine),with 63 cases in each group.The pain scores after anesthesia,the changes of patients'signs and stress indicators during anesthesia treatment were com-pared between the two groups.Results The pain scores of the study group at different time periods(1 h,2 h,4 h,6 h)were(1.18±0.05)points,(2.34±0.08)points,(2.47±0.19)points,and(3.15±0.48)points,respectively,which were lower than control group's(1.24±0.04)points,(2.42±0.12)points,(2.68±0.24)points,(3.32±0.42)points,the differ-ences were statistically significant(t=7.437,4.402,5.445,2.115,all P<0.05).Before anesthesia,there was no statisti-cally significant difference in blood pressure and heart rate between the two groups(both P>0.05).Immediately after anesthesia and at the end of operation,the diastolic blood pressure,systolic blood pressure and heart rate in the study group were lower than those in the control group,and the differences were statistically significant(all P<0.05).Imme-diately after anesthesia and at the end of operation,the stress indexes in the study group was better than that in the control group,and the difference was statistically significant(P<0.05).Conclusion The use of ropivacaine anesthetic drug with 0.20%concentration can reduce the pain score,effectively improve the final anesthetic effect,ensure the level of patients'signs and indicators,reduce stress indicators,ensure the smooth progress of surgical treatment,and achieve the final treatment purpose,which has clinical reference significance.

RopivacaineAnesthesiaPainStress indexAnesthetic effect

秦美英、田玲玲、孙秋艳

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单县中心医院麻醉科,山东 菏泽 274300

罗哌卡因 麻醉 疼痛 应激指标 麻醉效果

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(18)
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