Exploring the Efficacy of Different Simultaneous Fluid Resuscitation Therapy in Patients with Non-severe Acute Pancreatitis
Objective To explore the efficacy of fluid resuscitation at different time points in patients with non-severe acute pancreatitis.Methods Clinical data of 80 patients with non-severe acute pancreatitis treated in Yantai Yeda Hospital from May 2020 to May 2023 were retrospectively selected.According to the different time of fluid resuscita-tion,the patients were divided into control group and observation group,with 40 cases in each group.Patients in the control group received fluid resuscitation within 12 hours after the onset of abdominal pain,and patients in the obser-vation group received fluid resuscitation within 8 hours after the onset of abdominal pain.The differences in treatment effects between the two groups were compared and analyzed.Results The recovery time of vital signs,fasting/no drink-ing time and hospitalization time of patients in observation group were shorter than those in control group,and the dif-ferences were statistically significant(all P＜0.05).The incidence of multiple organ failure in the observation group(2.50%)was lower than that in the control group(15.00%),and the difference was statistically significant(P＜0.05).There was no significant difference in the incidence of interventional therapy,systemic inflammatory response and me-chanical ventilation between the two groups(all P＞0.05).After treatment,the levels of serum creatinine and urea nitro-gen were increased,and the levels of amylase and C-reactive protein were decreased in both groups,the indexes level of the observation group were better than those of the control group,and the differences were statistically significant(all P＜0.05).Conclusion Patients with non-severe acute pancreatitis receiving fluid resuscitation within 8 hours of the onset of abdominal pain have a significant value in promoting rapid relief of symptoms,improving clinical outcomes and peripheral blood biochemical indicators.
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