首页|阴道镜联合LEEP术在子宫颈癌前病变患者中的临床价值研究

阴道镜联合LEEP术在子宫颈癌前病变患者中的临床价值研究

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目的 探究阴道镜联合宫颈环形电切术(Loop Electrosurgical Excision Procedure,LEEP)对子宫颈癌前病变的临床价值.方法 方便选取2022年1月—2023年9月睢宁县妇幼保健院收治的103例子宫颈癌前病变患者为研究对象,采用密闭信封法分为对照组(n=51)、研究组(n=52).对照组行宫颈微波治疗,研究组行阴道镜联合LEEP术治疗.对比两组患者手术指标,并发症发生率,术前及术后3 d炎症因子,术前及术后3个月生活质量.结果 研究组手术时间(22.63±3.52)min,术中出血量(16.83±2.78)mL,住院时间(4.25±0.91)d,均优于对照组,差异有统计学意义(t=17.059、12.119、8.432,P均<0.001).术前,两组患者炎症因子水平对比,差异无统计学意义(P>0.05);术后 3 d,研究组炎症因子水平均低于对照组,差异有统计学意义(P<0.001).研究组并发症发生率低于对照组,差异有统计学意义(P<0.05).术前,两组患者生活质量评分对比,差异无统计学意义(P>0.05);术后3个月,研究组生活质量评分高于对照组,差异有统计学意义(P<0.05).结论 子宫颈癌前病变以阴道镜联合LEEP术治疗,可改善手术指标,控制炎症反应,加快患者术后恢复,从而提高患者生活质量,具有较高安全性.
Clinical Value of Colposcopy Combined with LEEP Surgery in Patients with Precancerous Lesions of the Cervix
Objective To explore the clinical value of colposcopy combined with Loop Electroresection Procedure(LEEP)in patients with precancerous lesions of the cervix.Methods A total of 103 patients with cervical precancerous lesions admitted to Suining Maternal and Child Health Hospital from January 2022 to September 2023 were conve-niently selected as the study objects.They were divided into control group(n=51)and study group(n=52)by using sealed envelope method.The control group received cervical microwave treatment,while the study group received col-poscopy combined with LEEP surgery.Surgical indexes,complication rate,inflammatory factors before and 3 days af-ter surgery,quality of life before and 3 months after surgery were compared between the two groups.Results The op-eration time of the study group was(22.63±3.52)min,the amount of intraoperative blood loss was(16.83±2.78)mL,and the length of hospital stay was(4.25±0.91)d,which were better than those of the control group,the differences were statistically significant(t=17.059,12.119,8.432,all P<0.001).Before operation,there was no statistically signifi-cant difference in the levels of various inflammatory factors between the two groups(P>0.05).3 days after surgery,the level of inflammatory factor in the study group was lower than that in the control group,and the difference was statisti-cally significant(P<0.001).The complication rate of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Before surgery,there was no significant difference in quality of life score between the two groups(P>0.05).Three months after operation,the quality of life score of the study group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion Colposcopy combined with LEEP in the treatment of cervical precancerous lesions can improve surgical indexes,control inflamma-tory response,accelerate postoperative recovery,improve patients'quality of life,and have high safety.

ColposcopyLoop electrosurgical excision procedurePrecancerous lesions of cervical cancerInflammatory responseSurgical indexQuality of life

陈敏、郑世琴、张梅

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睢宁县妇幼保健院妇产科,江苏 睢宁 212200

阴道镜 宫颈环形电切术 子宫颈癌前病变 炎症反应 手术指标 生活质量

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(19)
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