Analysis and Exploration of 40 Clinical Cases of Severe Pneumonia Treated with Liquid Purification
Objective To explore the effectiveness of blood purification therapy in patients with severe pneumonia.Methods A total of 40 patients with severe pneumonia admitted to the intensive care unit of Tianzhu County People's Hospital of Guizhou Province from January 2021 to December 2023 were simple randomly selected as the research ob-jects.According to the difference of treatment plan,they were divided into reference group and study group,with 20 cases in each group.The reference group was treated with routine treatment mode,and the study group was treated with blood purification therapy on the basis of routine treatment.The blood gas index,inflammation level,immune function and Acute Physiology and Chronic Health Evaluation score of the two groups were compared.Results partial pressure of oxygen and oxygenation index in the study group were higher than those in the reference group,and par-tial pressure of carbon dioxide was lower than that in the reference group,the differences were statistically significant(all P<0.05).The levels of interleukin-6(8.5±1.4)pg/mL and tumor necrosis factor-α(305.38±70.61)pg/mL in the study group were lower than those in the reference group,and the differences were statistically significant(t=6.438,3.419,both P<0.05).The Acute Physiology and Chronic Health Evaluation score of the study group was lower than that of the reference group,and the difference was statistically significant(P<0.05).Conclusion In the clinical treat-ment of severe pneumonia patients,not only conventional treatment plans can be implemented,but also blood purifi-cation therapy can be applied to improve clinical indicators and enhance treatment effectiveness.
Intensive care unitSevere pneumoniaBlood purification