首页|沙丁胺醇联合布地奈德治疗哮喘和慢阻肺重叠综合征的临床疗效分析

沙丁胺醇联合布地奈德治疗哮喘和慢阻肺重叠综合征的临床疗效分析

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目的 分析沙丁胺醇联合布地奈德治疗哮喘和慢性阻塞性肺疾病(简称慢阻肺)重叠综合征的临床疗效.方法 随机选取2022年1月—2023年11月济南市第一人民医院收治的84例哮喘和慢阻肺重叠综合征患者作为研究对象,按照抽签法分为研究组和对照组,每组42例.研究组行沙丁胺醇联合布地奈德治疗,对照组采用沙丁胺醇治疗.比较两组病情转归情况、肺功能、炎症因子水平、症状消失时间和生活质量评分.结果 研究组病情转归情况评分(21.02±3.89)分,高于对照组的(17.24±4.25)分,差异有统计学意义(t=4.251,P<0.001).治疗前,两组哮喘评估测试评分、肺功能指标、炎症因子水平、症状消失时间和生活质量评分相比,差异无统计学意义(P均>0.05);治疗后,研究组各项肺功能指标、生活质量评分均高于对照组,炎症因子水平、症状消失时间均低于对照组,差异有统计学意义(P均<0.05).结论 为哮喘和慢阻肺重叠综合征患者实施沙丁胺醇联合布地奈德治疗效果确切,能够更好地稳定患者病情,改善患者肺功能,提高患者生活质量.
Clinical Efficacy Analysis of Salbutamol Plus Budesonide in Asthma and COPD Overlap Syndrome
Objective To evaluate the clinical efficacy of salbutamol and budesonide in asthma and COPD overlap syndrome.Methods A total of 84 patients with asthma and COPD overlap syndrome admitted to the First People's Hospital of Jinan from January 2022 to November 2023 were randomly selected as the research objects.According to the lottery method,they were divided into study group and control group,with 42 cases in each group.The study group was treated with salbutamol combined with budesonide,and the control group was treated with salbutamol.The dis-ease outcome,lung function,inflammatory factor level,symptom disappearance time and quality of life score were compared between the two groups.Results The disease outcome score of the study group was(21.02±3.89)points,which was higher than that of the control group(17.24±4.25)points,and the difference was statistically significant(t=4.251,P<0.001).Before treatment,there was no significant difference in Asthma Control Test score,lung function in-dex,inflammatory factor level,symptom disappearance time and quality of life score between the two groups(all P>0.05);after treatment,the lung function indexes and quality of life scores of the study group were higher than those of the control group,and the levels of inflammatory factors and symptom disappearance time were lower than those of the control group,the differences were statistically significant(all P<0.05).Conclusion The effect of salbutamol combined with budesonide in patients with asthma and chronic obstructive pulmonary overlap syndrome is definite,which can better stabilize the patient's condition,improve the patient's lung function and improve the patient's quality of life.

Asthma and COPD overlap syndromeSalbutamolBudesonideClinical efficacy

赵衍栋、钱鑫、秦娜娜

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济南市第一人民医院呼吸内科,山东 济南 250011

哮喘和慢阻肺重叠综合征 沙丁胺醇 布地奈德 临床疗效

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(19)
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