冠心病合并慢性心力衰竭应用美托洛尔缓释片联合曲美他嗪治疗的效果及对患者生存质量的改善分析
The Effect Analysis of Metoprolol Sustained-release Tablets Combined with Trimetazidine in the Treatment of Coronary Heart Disease Compli-cated with Chronic Heart Failure and the Improvement of Patients'Qual-ity of Life
徐德华 1龚婷梅 1张志扬1
作者信息
- 1. 安溪县医院心内科,福建 泉州 362400
- 折叠
摘要
目的 研究冠状动脉粥样硬化性心脏病(Coronary Atherosclerotic Heart Disease,CHD)合并慢性心力衰竭(Chronic Heart Failure,CHF)患者联合使用美托洛尔缓释片、曲美他嗪的临床作用.方法 方便选取2021年6月—2023年6月安溪县医院收治的72例CHD合并CHF的患者为研究对象,以随机数表法分为对照组和观察组,各36例.对照组单用美托洛尔缓释片,观察组予以美托洛尔缓释片与曲美他嗪联合治疗,对比两组方案疗效、心功能以及生存质量.结果 观察组总有效率(94.44%)高于对照组(77.78%),差异有统计学意义(χ2=4.180,P=0.040).治疗后,观察组心功能指标值优于对照组,差异有统计学意义(P<0.05).治疗后,观察组生存质量量表得分高于对照组,差异有统计学意义(P<0.05).结论 美托洛尔缓释片及曲美他嗪两药联合治疗能够提升CHD合并CHF患者的用药疗效,恢复其心功能,并改善其生存质量.
Abstract
Objective To study the clinical effect of metoprolol sustained-release tablets and trimetazidine in patients with coronary atherosclerotic heart disease(CHD)complicated with chronic heart failure(CHF).Methods A total of 72 patients with CHD complicated with CHF admitted to Anxi County Hospital from June 2021 to June 2023 were conve-niently selected as study objects and divided into control group and observation group by random number table method,36 cases in each group.The control group was treated with metoprolol sustained-release tablets alone,and the observation group was treated with metoprolol sustained-release tablets combined with trimetazidine.The efficacy,cardiac function and quality of life of the two groups were compared.Results The total effective rate of the observation group(94.44%)was higher than that of the control group(77.78%),and the difference was statistically significant(χ2=4.180,P=0.040).After treatment,the cardiac function indexes of the observation group was better than those of the control group,and the difference was statistically significant(P＜0.05).After treatment,the score of the Quality of Life Scale in the observation group was higher than those in the control group,and the difference was statistically signifi-cant(P＜0.05).Conclusion The combination of metoprolol sustained-release tablets and trimetazidine can improve the efficacy of CHD patients with CHF,better restore their cardiac function and improve their quality of life.
关键词
冠心病/慢性心力衰竭/美托洛尔缓释片/曲美他嗪/生存质量Key words
Coronary heart disease/Chronic heart failure/Metoprolol sustained release tablets/Trimetazidine/Quality of Life引用本文复制引用
出版年
2024
NETL
NSTL
万方数据