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血管源性脑白质病变的视网膜成像研究进展

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血管源性脑白质病变(White Matter Lesions,WMLs)在老年人群中发病率高,往往引起血管性认知障碍和痴呆.视网膜血管在胚胎学起源和解剖结构上类似于脑小血管,而视网膜神经纤维层又是大脑的延伸白质.近年来越来越多的研究证实WMLs可引起视网膜改变,本综述总结了现有的研究结果,概述了WMLs患者视网膜成像临床研究现状,以期指导临床对WMLs的筛查和预防.
Progress in Clinical Research on Retinal Imaging in Vascular White Mat-ter Lesions
The incidence of vascular white matter lesions(WMLs)is high in the elderly population,which often causes vascular cognitive impairment and dementia.Retinal blood vessels are similar to brain small blood vessels in embryological origin and anatomical structure,and the retinal nerve fiber layer is the extended white matter of the brain.In recent years,a growing number of studies have substantiated that WMLs can cause retinal changes.This ar-ticle reviewed the existing research results and summarizes the current clinical research status of retinal imaging in pa-tients with WMLs,with a view to guiding clinical screening and prevention.

White matter lesionsVascular cognitive impairmentCerebral small vessel diseaseRetinal imagingRetina nerve fiber layerRetinal vessel

陶锐、赵婕、周育、周慧

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上海理工大学附属市东医院眼科,上海 200438

上海理工大学附属市东医院神经内科,上海 200438

脑白质病变 血管性认知障碍 脑小血管病 视网膜成像 视网膜神经纤维层 视网膜血管

上海市卫生健康委青年基金

20204Y0021

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(19)
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