Objective To investigate the effect of different ovulation induction regimens in patients with Diminished Ovarian Reserve.Methods From June 2022 to December 2023,40 patients with diminished ovarian reserve undergo-ing in vitro fertilization-embryo transfer(IVF-ET)in Qiandongnan Miao and Dong Autonomous Prefecture Traditional Chinese Medicine Hospital were simple randomly selected as the research objects.According to different ovulation in-duction schemes,they were divided into microstimulation group and progestin primed ovarian stimulation(PPOS)scheme group,with 20 cases in each group.Ovulation induction and embryo status,serum estrogen[progesterone(P),estradiol(E2),luteinising hormone(LH)]levels and clinical outcomes of the two groups were compared.Results The early LH peak rate in the microstimulation group(30.00%)was higher than that in the PPOS group(0),and the differ-ence was statistically significant(χ2=4.902,P=0.027).On the day of human chorionic gonadotrophin(HCG)injection,serum LH in the microstimulation group was higher than that in the PPOS group,and the difference was statistically significant(P<0.05),while there was no statistically significant difference in serum E2 and P levels between the two groups(both P>0.05).There was no significant difference in embryo implantation rate,biochemical pregnancy rate and clinical pregnancy rate between the two groups(all P>0.05).Conclusion There is no significant difference in clinical outcomes between microstimulation and PPOS in patients with ovarian reserve decline,while PPOS can reduce the in-cidence of early LH peak.
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