Analysis of the Effects of Different Ovulation Induction Regimens on Pa-tients with Diminished Ovarian Reserve
Objective To investigate the effect of different ovulation induction regimens in patients with Diminished Ovarian Reserve.Methods From June 2022 to December 2023,40 patients with diminished ovarian reserve undergo-ing in vitro fertilization-embryo transfer(IVF-ET)in Qiandongnan Miao and Dong Autonomous Prefecture Traditional Chinese Medicine Hospital were simple randomly selected as the research objects.According to different ovulation in-duction schemes,they were divided into microstimulation group and progestin primed ovarian stimulation(PPOS)scheme group,with 20 cases in each group.Ovulation induction and embryo status,serum estrogen[progesterone(P),estradiol(E2),luteinising hormone(LH)]levels and clinical outcomes of the two groups were compared.Results The early LH peak rate in the microstimulation group(30.00%)was higher than that in the PPOS group(0),and the differ-ence was statistically significant(χ2=4.902,P=0.027).On the day of human chorionic gonadotrophin(HCG)injection,serum LH in the microstimulation group was higher than that in the PPOS group,and the difference was statistically significant(P<0.05),while there was no statistically significant difference in serum E2 and P levels between the two groups(both P>0.05).There was no significant difference in embryo implantation rate,biochemical pregnancy rate and clinical pregnancy rate between the two groups(all P>0.05).Conclusion There is no significant difference in clinical outcomes between microstimulation and PPOS in patients with ovarian reserve decline,while PPOS can reduce the in-cidence of early LH peak.
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