首页|探讨应用布地奈德联合纤维支气管镜肺泡灌洗治疗小儿难治性肺炎支原体肺炎的效果

探讨应用布地奈德联合纤维支气管镜肺泡灌洗治疗小儿难治性肺炎支原体肺炎的效果

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目的 探究小儿难治性肺炎支原体肺炎患儿采取布地奈德联合纤维支气管镜(简称纤支镜)肺泡灌洗治疗的临床治疗效果.方法 回顾性选取2023年6月—2024年1月漳州正兴医院收治的110例小儿难治性肺炎支原体肺炎患儿的临床资料,按照不同治疗方法将患儿分为对照组(55例,单纯雾化治疗)和观察组(55例,纤支镜肺泡灌洗治疗).比较两组患儿的临床指标、肺功能指标、并发症.结果 观察组的发热持续时间为(6.03±1.69)d,咳嗽缓解时间为(7.76±1.09)d,哮鸣音消退时间为(6.76±1.18)d,住院时间为(6.37±1.09)d,均短于对照组,差异有统计学意义(t=6.734、8.188、5.321、7.721,P均<0.05).第1秒用力呼气容积为(2.79±0.69)mL,用力肺活量为(2.97±0.78)mL,最大呼气流量为(3.86±1.03)mL,均高于对照组,差异有统计学意义(t=11.903、9.201、7.043,P均<0.05).观察组并发症总发生率为1.82%,低于对照组,差异有统计学意义(χ2=4.356,P<0.05).结论 采取布地奈德纤支镜肺泡灌洗治疗小儿难治性肺炎支原体肺炎,能够有效改善患儿症状,促进肺功能恢复,缩短治疗时间,提高临床治疗安全性.
Exploring the Effect of Budesonide Combined with Fiberoptic Bronchos-copy Alveolar Lavage in the Treatment of Pediatric Refractory Myco-plasma Pneumoniae Pneumonia in Children
Objective To explore the clinical effect of budesonide combined with fiberoptic bronchoscopy(referred to as fiberscope)alveolar lavage in children with pediatric refractory mycoplasma pneumoniae pneumonia.Methods The clinical data of 110 children with pediatric refractory mycoplasma pneumoniae pneumonia admitted to Zhangzhou Zhengxing Hospital from June 2023 to January 2024 were retrospectively selected.According to different treatment methods,they were divided into control group(55 cases,simple atomization treatment)and observation group(55 cases,fiberoptic bronchoscopy alveolar lavage).The clinical indexes,pulmonary function indexes and complications were compared between children in two groups.Results The duration of fever in the observation group was(6.03±1.69)d,the cough relief time was(7.76±1.09)d,the wheezing sound regression time was(6.76±1.18)d,and the hospitaliza-tion time was(6.37±1.09)d,which were both shorter than those of the control group,the differences were statistically significant(t=6.734,8.188,5.321,7.721,all P<0.05).The forced expiratory volume in the first second was(2.79±0.69)mL,the forced vital capacity was(2.97±0.78)mL,and the peak expiratory flow was(3.86±1.03)mL,which were both higher than those in the control group,and the differences were statistically significant(t=11.903,9.201,7.043,all P<0.05).The total incidence of complications in the observation group was 1.82%,which was lower than that in the control group,the difference was statistically significant(χ2=4.356,P<0.05).Conclusion Budesonide fiberoptic bron-choscopy alveolar lavage in the treatment of pediatric refractory mycoplasma pneumoniae pneumonia in children can effectively improve the symptoms of children,promote the recovery of lung function,shorten the treatment time and im-prove the safety of clinical treatment.

BudesonideFiberoptic bronchoscopy alveolar lavagePediatric refractory mycoplasma pneumoniae pneumonia in childrenDuration of hospitalization

吴倩倩、彭斌、郑庆峰

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漳州正兴医院新生儿科,福建 漳州 363000

布地奈德 纤维支气管镜肺泡灌洗 小儿难治性肺炎支原体肺炎 住院时间

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(20)