Effect of Oral Nutrition Supplement on the Efficacy and Adverse Reac-tions of Esophageal Cancer Patients Undergoing Concurrent Radiotherapy and Chemotherapy
Objective To explore the effect of oral nutrition supplement and its impact on adverse reactions in the treatment of esophageal cancer patients undergoing concurrent radiotherapy and chemotherapy.Methods A total of 100 patients with esophageal cancer undergoing concurrent chemoradiotherapy admitted to Liaocheng People's Hospi-tal from July 2022 to July 2023 were randomly selected as the research objects.They were divided into two groups by different treatment methods.The control group(50 cases)received routine nutritional treatment,and the observation group(50 cases)received routine plus enteral nutrition support treatment.The therapeutic effects,nutritional level,im-mune function and adverse reactions of the two groups were compared.Results The objective response rate and dis-ease control rate of the observation group were 54.00%(27/50)and 94.00%(47/50),respectively,which were higher than 34.00%(17/50)and 80.00%(40/50)of the control group,and the differences were statistically significant(χ2=4.058,4.332,both P<0.05).The body mass index,serum total protein,prealbumin and albumin in the observation group were higher than those in the control group,and the differences were statistically significant(all P<0.05).The levels of immunoglobulin A,immunoglobulin G and immunoglobulin M in the observation group were higher than those in the control group,and the differences were statistically significant(all P<0.05).The incidence of adverse reac-tions in the observation group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion For patients with esophageal cancer undergoing concurrent chemoradiotherapy,oral nutrition supplementation is helpful to improve the efficacy,nutritional status and immune function.
Oral nutrition supplementEsophageal cancer concurrent chemoradiotherapyTreatment effectAdverse reactions
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维普
