Analysis of the Efficacy of Ambroxol Hydrochloride+Azithromycin in Children with Mycoplasma Pneumonia Complicated with Acute Bronchitis
Objective To explore the therapeutic effect of ambroxol hydrochloride+azithromycin on mycoplasma pneumonia complicated with acute bronchitis in children and its effect on the levels of procalcitonin(PCT),interferon-γ(IFN-γ)and serum hypersensitive C-reactive protein(hs-CRP).Methods A total of 120 children with mycoplasma pneumonia complicated with acute bronchitis admitted to Qingyang Hospital of Traditional Chinese Medicine from De-cember 2022 to December 2023 were randomly selected as the research objects.According to the different treatment methods,they were divided into control group and observation group,with 60 cases in each group.The control group was treated with azithromycin,and the observation group was treated with ambroxol hydrochloride+azithromycin.The inflammatory response,symptom improvement time and hospitalization time,lung function,blood gas index,quality of life of the two groups were compared.Results After treatment,PCT was(3.99±1.56)μg/L,IFN-γ was(9.56±4.26)ng/L and hs-CRP was(12.59±5.01)mg/L in the observation group,which were lower than(7.02±2.01)μ g/L,(18.59±5.24)ng/L and(20.02±5.95)mg/L in the control group,and the differences were statistically significant(t=9.224,10.357,7.399,all P＜0.05).The symptom improvement time and hospitalization time of the observation group were shorter than those of the control group,and the differences were statistically significant(both P＜0.05).After treatment,the lung function and blood gas indexes of the observation group were better than those of the control group,and the differences were statistically significant(both P＜0.05).After treatment,the quality of life score of the observation group was higher than that of the control group,and the difference was statistically significant(P＜0.05).Conclusion In the treatment of mycoplasma pneumonia complicated with acute bronchitis in children,the combination of ambroxol hydrochloride and azithromycin can significantly regulate the inflammatory state of children,shorten the time of symp-tom improvement and hospitalization,and improve the lung function of children.
Mycoplasma pneumonia in childrenAcute bronchitisAmbroxol hydrochlorideAzithromycinTherapeutic effect
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维普
