Analysis of the Effect of Ciprofol Application on the Circulatory System During Anesthesia Induction of Surgery in Elderly Patients with Colorec-tal Cancer
Objective To analyze the effect of the application of ciprofol on the circulatory system of elderly patients with colorectal cancer during the induction of surgery.Methods A total of 116 elderly patients who underwent colorec-tal cancer surgery in Wujin Hospital Affiliated to Jiangsu University from January 2022 to June 2023 were conve-niently selected as the study subjects.The patients were divided into two groups different anesthesia induction meth-ods,with 58 cases in each group.The control group was induced by propofol anesthesia,and the observation group was induced by ciprofol anesthesia.The postoperative cognitive function,hemodynamic status,anesthesia induction time and postoperative recovery were compared between the two groups.Results The scores of cognitive function in the observation group were higher than those in the control group at 10 min and 30 min after operation,and the differ-ences were statistically significant(both P＜0.05).There was no significant difference in cognitive function score be-tween the two groups at 2 hours after operation(P＞0.05).There was no significant difference in diastolic blood pres-sure,systolic blood pressure and heart rate between the two groups before injection(all P＞0.05).The hemodynamic in-dexes of the observation group were lower than those of the control group at the time of intubation,extubation and the end of operation,and the differences were statistically significant(all P＜0.05).There was no significant difference in anesthesia induction time between the two groups(P＞0.05).The recovery time of the observation group was(4.01±0.65)min,and the recovery time of directional force was(4.13±1.02)min,which was shorter than(5.02±1.21)min,(5.67±1.25)min of the control group,the differences were statistically significant(t=5.600,7.270,both P＜0.05).Con-clusion Compared with propofol,the application of ciprofol in the induction of anesthesia in elderly patients with colorectal cancer can improve the postoperative cognitive function of patients,regulate the hemodynamic level of pa-tients,and shorten the recovery time of postoperative recovery and orientation.It has high clinical reference value.
Elderly patientsColorectal cancer surgeryAnesthesia inductionCiprofolCirculatory systemSecurity
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