Objective To compare the inflammatory level and lung function indexes of elderly patients with acute exac-erbation of chronic obstructive pulmonary disease(AECOPD)with different traditional Chinese medicine syndromes.Methods A total of 160 elderly patients with AECOPD admitted to Longyan First Hospital,Affiliated to Fujian Medi-cal University from October 2021 to October 2023 were prospective randomly selected as the research objects.Accord-ing to different traditional Chinese medicine syndromes,they were divided into phlegm-turbidity obstructing lung group(n=29),phlegm-heat obstructing lung group(n=62),phlegm-stasis obstructing lung group(n=21)and lung-kidney deficiency group(n=48).The course of disease,number of acute exacerbations within 1 year,inflammation level and lung function indexes of the four groups were compared.Results The course of disease in the lung-kidney deficiency group and the phlegm-stasis obstructing lung group were(12.68±3.86)years and(10.74±2.86)years,re-spectively,which were longer than(8.58±1.93)years and(8.62±1.75)years in the phlegm-turbidity obstructing lung group and the phlegm-heat obstructing lung group,and the difference was statistically significant(F=153.68,P<0.05).The number of acute exacerbations in the phlegm-turbidity obstructing lung group was less than that in the other three groups,the number of acute exacerbations in the lung-kidney deficiency group was more than that in the other three groups,and the number of acute exacerbations in the phlegm-stasis obstructing lung group was more than that in the phlegm-heat obstructing lung group,the difference were statistically significant(all P<0.05).The inflammatory factors in the phlegm-heat obstructing lung group were higher than those in the other three groups,and the differences were statistically significant(all P<0.05).The lung function index of the phlegm turbidity obstructing lung group was better than that of the other three groups,the lung function of the lung and kidney deficiency group was worse than that of the other three groups,and the lung function of the phlegm heat obstructing lung group was better than that of the phlegm stasis obstructing lung group,the differences were statistically significant(all P<0.05).Conclusion There is a significant difference between the inflammation level and lung function index of elderly AECOPD patients with tradi-tional Chinese medicine syndrome type,which may be a standard for predicting the degree of disease and evaluating the curative effect in clinical practice.
关键词
中医证型/慢性阻塞性肺疾病急性加重期/炎症/肺功能指标
Key words
Traditional Chinese Medicine syndromes/Acute exacerbation of chronic obstructive pulmonary disease/Inflammation/Lung function indexes
维普
万方数据