Analysis of the Effect of New Quadruple Therapy on Chronic Heart Fail-ure with Reduced Ejection Fraction
Objective To analyze the effect of new quadruple therapy in the clinical treatment of patients with chronic heart failure with reduced ejection fraction.Methods A total of 92 patients with chronic heart failure with reduced ejection fraction admitted to Wenshang County People's Hospital from January 2022 to April 2023 were conveniently selected as the research objects.According to the different treatment method,they were divided into control group and observation group,with 46 cases in each group.The control group used the"Golden Triangle"treatment plan,and the observation group used the new quadruple treatment plan to observe.The cardiac function indexes,plasma brain natri-uretic peptide,6-minute walking test distance,treatment effect and incidence of adverse reactions were compared be-tween the two groups.Results After treatment,the left ventricular end-diastolic diameter and left ventricular end-systolic diameter were(31.24±4.74)mm,(37.33±6.91)mm,respectively in the observation,which group were lower than(36.21±4.59)mm,(42.58±7.75)mm in the control group,and the left ventricular ejection fraction was(56.02±6.48)%,whichwas higher than(50.22±4.94)%in the control group,the differences were statistically significant(t=5.109,3.429,4.828,all P<0.05).After treatment,the level of plasma brain natriuretic peptide in the observation group was lower than that in the control group,and the 6-minute walking test distance was longer than that in the control group,the differences were statistically significant(both P<0.05).The total effective rate of treatment in the observa-tion group was higher than that of the control group,the different was statistically significant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The effect of new quadruple therapy in patients with chronic heart failure with low ejection fraction is better,which can improve the cardiac function and reduce the level of plasma brain natriuretic peptide.
万方数据
维普
