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阿托伐他汀治疗心肌梗死后无症状心衰患者的临床疗效分析

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目的 探究阿托伐他汀治疗心肌梗死后无症状心衰患者的临床疗效.方法 方便选取2021年9月—2023年2月吉林省人民医院心内科收治的134例心肌梗死患者为研究对象,依据不同治疗方法分为两组,对照组(n=67)予以常规治疗,观察组(n=67)予以阿托伐他汀治疗,比较两组患者心功能指标、不良反应发生情况及生活质量评分.结果 治疗前,两组患者左心室射血分数、左心室舒张末期内径及左心室收缩末期内径比较,差异无统计学意义(P均>0.05);治疗后,观察组左心室射血分数高于对照组,左心室舒张末期内径及左心室收缩末期内径均低于对照组,差异有统计学意义(P均<0.05).观察组不良反应发生率为7.46%(5/67),低于对照组的19.40%(13/67),差异有统计学意义(χ2=4.107,P=0.043).治疗前,两组患者生活质量评分比较,差异无统计学意义(P>0.05);治疗后,观察组生活质量评分高于对照组,差异有统计学意义(P<0.05).结论 应用阿托伐他汀治疗心肌梗死后无症状心力衰竭患者临床疗效较好,有助于进一步缓解患者的基本症状.
Clinical Efficacy Analysis of Atorvastatin in the Treatment of Asymptom-atic Heart Failure Patients after Myocardial Infarction
Objective To explore the clinical efficacy of atorvastatin in the treatment of asymptomatic heart failure pa-tients after myocardial infarction.Methods In this study,134 patients with myocardial infarction admitted to the De-partment of Cardiology at Jilin Province People's Hospital from September 2021 to February 2023 were conveniently selected as the study objects and divided into two groups according to different treatment methods,control group(n=67)receiving conventional treatment and observation group(n=67)receiving atorvastatin treatment.Cardiac function indexes,adverse reactions and quality of life scores were compared between the two groups.Results Before treatment,there were no significant differences in left ventricular ejection fraction,left ventricular end-diastolic diameter and left ventricular end-systolic diameter between the two groups(all P>0.05);after treatment,left ventricular ejection fraction in observation group was higher than control group,and left ventricular end-diastolic diameter and left ven-tricular end-systolic diameter were lower than control group,the differences were statistically significant(all P<0.05).The incidence of adverse reactions in the observation group was 7.46%(5/67),lower than that in the control group 19.40%(13/67),the difference was statistically significant(χ2=4.107,P=0.043).Before treatment,there was no signifi-cant difference in quality of life scores between the two groups(P>0.05);after treatment,the life quality score of the observation group was higher than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The clinical effect of atorvastatin in the treatment of asymptomatic heart failure after myocardial infarction is better,which is helpful to further relieve the basic symptoms of patients.

AtorvastatinMyocardial infarctionAsymptomaticHeart failure

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吉林省人民医院心内科,吉林 长春 130000

阿托伐他汀 心肌梗死 无症状 心衰

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(23)