中外医疗2024,Vol.43Issue(23) :95-98.DOI:10.16662/j.cnki.1674-0742.2024.23.095

卡贝缩宫素在预防妊娠期高血压患者剖宫产产后出血的疗效

The Efficacy of Carbetocin in Preventing Postpartum Hemorrhage after Cesarean Section in Patients with Gestational Hypertension

施桂丽 黄婷婷 章琳
中外医疗2024,Vol.43Issue(23) :95-98.DOI:10.16662/j.cnki.1674-0742.2024.23.095

卡贝缩宫素在预防妊娠期高血压患者剖宫产产后出血的疗效

The Efficacy of Carbetocin in Preventing Postpartum Hemorrhage after Cesarean Section in Patients with Gestational Hypertension

施桂丽 1黄婷婷 1章琳1
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作者信息

  • 1. 泉州市妇幼保健院·儿童医院产科,福建 泉州 362000
  • 折叠

摘要

目的 探究妊娠期高血压孕妇在剖宫产手术治疗中使用卡贝缩宫素对产后出血的预防效果.方法 回顾性选取2022年3月—2023年8月泉州市妇幼保健院·儿童医院收治的88例妊娠期高血压患者的临床资料,根据产后出血预防用药方式的差异分为两组,每组44例.常规组予以传统缩宫素,观察组予以卡贝缩宫素.分析对比两组患者产后出血状况、产后24 h血红蛋白降低值、不良反应发生情况.结果 观察组产后24 h出血量(567.24±32.21)mL,产后24 h血红蛋白降低值(10.24±1.36)g/L,均低于常规组的(732.24±64.24)mL、(19.24±2.50)g/L,差异有统计学意义(t=12.341、12.540,P均<0.05).观察组不良反应总发生率为4.55%(2/44),低于常规组的18.18%(8/44),差异有统计学意义(χ2=4.602,P<0.05).结论 卡贝缩宫素应用在妊娠期高血压疾病患者中效果突出,对预防剖宫产手术后产后出血作用较好,能够保障产妇顺利分娩.

Abstract

Objective To explore the effect of carbetocin on preventive postpartum hemorrhage in gestational hyperten-sion patients after cesarean section.Methods The clinical data of 88 patients with gestational hypertension after admit-ted to Quanzhou Maternal and Child Health Hospital·Children's Hospital from March 2022 to August 2023 were retro-spectively selected and divided into two groups with 44 cases in each group according to the differences in the preven-tive medication methods for postpartum hemorrhage.The conventional group was given traditional oxytocin.The obser-vation group was given carbetocin.Postpartum hemorrhage,24 h postnatal hemoglobin reduction and adverse reactions were analyzed and compared between the two groups.Results The postpartum bleeding at 24 h in the observation group was(567.24±32.21)mL,and the decrease of hemoglobin at 24 h after delivery was(10.24±1.36)g/L,which were lower than that in the conventional group(732.24±64.24)mL,(19.24±2.50)g/L,the differences were statistically significant(t=12.341,12.540,both P<0.05).The total incidence of adverse reactions in the observation group was 4.55%(2/44),lower than that in the conventional group 18.18%(8/44),and the difference was statistically significant(χ2=4.602,P<0.05).Conclusion The application of carbetocin is effective in the patients with gestational hyperten-sion,and has a better effect on preventing postpartum hemorrhage after cesarean section,which can guarantee the smooth delivery of parturients.

关键词

卡贝缩宫素/妊娠期高血压/产后出血/剖宫产

Key words

Carbetocin/Gestational hypertension/Postpartum hemorrhage/Cesarean section

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出版年

2024
中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
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