Clinical Effect Analysis of Metronidazole,Nifuratel Nysfungin Vaginal Soft Capsules and Lactobacillus Vaginal Capsule Combined in the Treatment of Bacterial Vaginosis
Objective To investigate the efficacy of triple drug regimen(metronidazole+nifuratel nyysfungin vaginal soft capsules+lactobacillus vaginal capsule)in patients with bacterial vaginosis(BV).Methods A total of 66 patients with BV admitted to the Jinan First People's Hospital from August 2021 to December 2023 were conveniently selected as the research objects and divided into two groups according to different treatment methods,with 33 cases in each group.The control group was given metronidazole and nifuratel nysfungin soft capsule intervention;the study group was treated with lactobacillus vaginal capsules in addition to the above drugs.The clinical efficacy,vaginal environ-ment and adverse reactions were compared between the two groups.Results The total effective rate of treatment in the study group was 96.97%(32/33),which was higher than 78.79%(26/33)of the control group,and the difference was statistically significant(χ2=5.121,P=0.024).After treatment,the results of Lactobacillus,Staphylococcus,Bacteroides and pH in the study group were better than those in the control group,and the differences were statistically significant(all P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The combination of the three drugs not only has a good effect on BV but also has better safety,which is conducive to improving the effect of improving the vaginal environment of patients.
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