右美托咪定联合应用达克罗宁胶浆预防泌尿外科手术术后导尿管相关性膀胱刺激征的效果分析
Analysis of the Effect of Dexmedetomidine Combined with Dyclonine Muci-lage on Preventing Catheter Related Bladder Discomfort after Urological Surgery
李沅君 1姚福旺 2徐源1
作者信息
- 1. 山东大学齐鲁医院麻醉科,山东 济南 250012
- 2. 山东第二医科大学附属医院麻醉科,山东 潍坊 261033
- 折叠
摘要
目的 探讨在泌尿外科手术术后导尿管相关性膀胱刺激征(catheter related bladder discomfort,CRBD)的预防中联合使用右美托咪定和达克罗宁胶浆的临床效果.方法 随机选取2020年1月—2021年1月山东第二医科大学附属医院收治的80例拟在全身麻醉下行泌尿外科手术的男性患者为研究对象,根据不同治疗方案分为研究组和对照组,各40例.全麻诱导前均给予两组患者1 µg/kg右美托咪定,10～15 min内泵注完毕.研究组在尿管插入前经尿道注射达克罗宁胶浆5 mL,并用达克罗宁胶浆润滑导尿管;对照组则注入等容积0.9%生理盐水,并用石蜡油润滑导尿管进行导尿.比较两组患者苏醒质量和CRBD发生率.结果 研究组术后CRBD发生率为0,低于对照组的15.00%(6/40),差异有统计学意义(χ2=4.505,P<0.05).研究组拔管后1 h的视觉模拟评分、躁动评分均低于对照组,Ramsay镇静评分高于对照组,差异有统计学意义(P均<0.05).结论 在泌尿外科手术术后CRBD的预防中,右美托咪定和达克罗宁胶浆的联合应用临床效果更好,可减轻患者术后疼痛和躁动表现,实用性和安全性更高.
Abstract
Objective To investigate the clinical effect of dexmedetomidine combined with dyclonine mucilage in the prevention of catheter related bladder discomfort(CRBD)after urological surgery.Methods A total of 80 male patients undergoing urological surgery under general anesthesia admitted to the Affiliated Hospital of Shandong Second Medi-cal University from January 2020 to January 2021 were randomly selected as the research objects.According to differ-ent treatment schemes,they were divided into study group and control group,with 40 cases in each group.Both groups were given 1 µg/kg dexmedetomidine before induction of general anesthesia,and the infusion was completed within 10-15 min.In the study group,5 mL of dyclonine mucilage was injected transurethrally before the catheter was inserted,and the catheter was lubricated with dyclonine mucilage.The control group was injected with an equal volume of 0.9%normal saline,and the catheter was lubricated with paraffin oil for catheterization.The quality of recovery and the inci-dence of CRBD were compared between patients in two groups.Results The incidence of CRBD in the study group was 0,which was lower than 15.00%(6/40)in the control group,and the difference was statistically significant(χ2=4.505,P<0.05).The Visual Analogue Score and agitation score of the study group 1 h after extubation were lower than those of the control group,and the Ramsay sedation score was higher than that of the control group,the differences were statistically significant(all P<0.05).Conclusion In the prevention of CRBD after urological surgery,the combina-tion of dexmedetomidine and dyclonine mucilage has a better clinical effect,which can reduce postoperative pain and restlessness,and has higher practicability and safety.
关键词
右美托咪定/达克罗宁胶浆/泌尿外科手术/导尿管相关性膀胱刺激征/苏醒质量/血流动力学Key words
Dexmedetomidine/Dyclonine/Urinary surgery/Catheter-related bladder discomfort/Awakening quality/Hemodynamics引用本文复制引用
出版年
2024
NETL
NSTL
万方数据