Effect of Minimally Invasive Drilling and Drainage Combined with Atorv-astatin in Patients with Chronic Subdural Hematoma
Objective To investigate the effect of atorvastatin therapy on patients with chronic subdural hematoma af-ter minimally invasive trepanation and drainage.Methods Forty-eight patients with chronic subdural hematoma treated in Meitan County People's Hospital of Guizhou Province from May 2018 to May 2023 were conveniently se-lected as the study objects,and divided into the control group and the combination group according to different treat-ment methods,with 24 cases in each group.The control group received minimally invasive trephination and drainage and dexamethasone,and the combination group received oral atorvastatin therapy on the basis of the reference group.Residual hematoma volume,nerve function and daily living ability score,complication rate and recurrence rate were compared between the two groups.Results After 7 days,15 days,1 month and 3 months of treatment,the volume of re-sidual hematoma in the two groups was significantly lower than that before treatment,and the residual hematoma vol-ume in the combination group was less than that in the control group at each time point,and the differences were sta-tistically significant(all P<0.05).After treatment,the neurological function indexes and scores of the combination group were better than those of the control group,and the scores of daily living ability were higher than those of the control group,the differences were statistically significant(all P<0.05).The total incidence of postoperative complica-tions in the combination group was 4.17%(1/24),which was significantly lower than that in the control group 33.33%(8/24),the difference was statistically significant(χ2=4.923,P=0.027).The recurrence rate of the combination group was 4.17%(1/24),which was significantly lower than that of the control group 25.00%(6/24),the difference was statis-tically significant(χ2=4.181,P=0.041).Conclusion For patients with chronic subdural hematoma,the application of minimally invasive trepanation and drainage,combined with atorvastatin therapy after surgery,can not only improve nerve function and daily living ability,but also effectively reduce the amount of residual hematoma,reduce postopera-tive complications,and reduce the recurrence rate.
Neural functionChronic subdural hematomaMinimally invasive trepanation and drainageAtorvastatin
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