Analysis of the Efficacy of Dynamic Guidance of Shexiang Tongxin Diwan Combined with Amlodipine Besylate Tablets in Patients with Hypertension and Coronary Heart Disease Under the Concept of General Practice
Objective To analyze the therapeutic effect of dynamic guidance of Shexiang Tongxin Diwan combined with amlodipine besylate tablets in the treatment of patients with hypertension and coronary heart disease(CHD)un-der the general philosophy.Methods A total of 170 patients with hypertension and CHD admitted to Yongan Munici-pal Hospital from October 2020 to October 2022 were randomly selected as the study objects,and were divided into observation group(n=85)and control group(n=85)according to different treatment methods.Observation group was treated with Shexiang Tongxin dropping pills combined with amlodipine besylate tablets under the dynamic guidance of general practice,and control group was treated with amlodipine besylate tablets.Both groups were treated continu-ously for 3 months.The clinical efficacy,cardiac function[stroke volume(SV),left ventricular end diastolic dimension(LVEDD),left ventricular ejection fraction(LVEF)]and hemorheology indexes[low viscosity of whole blood,high vis-cosity of whole blood,fibrinogen(FIB)]before and after treatment were compared between the two groups.Results The effective rate of the observation group was 97.65%(83/85),which was higher than that of the control group 89.41%(76/85),the difference was statistically significant(χ2=4.763,P<0.05).Before treatment,there was no significant dif-ference in cardiac function index and hemorheology index between the two groups(both P>0.05);after treatment,LVEDD,whole blood viscosity of low cut and high cut,FIB and SV and LVEF in observation group were lower than those in control group,and the differences were statistically significant(all P<0.05).There was no significant differ-ence in the incidence of adverse reactions between the two groups(P>0.05).Conclusion The dynamic guidance of Shexiang Tongxin Diwan combined with amlodipine besylate tablets in patients with hypertension and CHD under the concept of general practice is more effective,and the combination of medication can significantly improve the cardiac function of patients,improve the hemorheology indexes of patients,and has high drug safety.
General practice conceptDynamic guidanceHypertension with coronary heart diseaseShexiang Tongxin DiwanAmlodipine besylate tablets
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