罗哌卡因复合右美托咪定椎旁神经阻滞在肺癌切除手术中的应用
Application of Ropivacaine Combined with Dexmedetomidine Paraverte-bral Nerve Block in Lung Cancer Resection Surgery
李艳媛 1施超蓉 1卢建朴1
作者信息
- 1. 石狮市医院麻醉科,福建 泉州 362700
- 折叠
摘要
目的 分析罗哌卡因复合右美托咪定椎旁神经阻滞在肺癌切除手术中的应用效果.方法 方便选取2022年1月—2023年12月石狮市医院收治的96例肺癌切除手术患者为研究对象,根据不同麻醉方法分为复合组、罗哌卡因组、全麻组,每组32例.复合组给予罗哌卡因复合右美托咪定椎旁神经阻滞,罗哌卡因组给予罗哌卡因椎旁神经阻滞,全麻组给予全身麻醉,对比3组患者的血流动力学、麻醉质量、不良反应、疼痛程度.结果 T1～T4,复合组心率、平均动脉压、血氧饱和度均优于罗哌卡因组和全麻组,差异有统计学意义(P均<0.05).复合组感觉阻滞起效时间、拔管时间、自主呼吸恢复时间、阻滞维持时间、瑞芬太尼用量、舒芬太尼用量均优于罗哌卡因组和全麻组,差异有统计学意义(P均<0.05).复合组不良反应总发生率为9.38%(3/32),低于罗哌卡因组的25.00%(8/32)和全麻组的31.25%(10/32),3组患者的不良反应总发生率对比,差异无统计学意义(P>0.05).术后2 h、6 h、12 h、24 h,复合组疼痛评分均低于罗哌卡因组和全麻组,差异有统计学意义(P均<0.05).结论 罗哌卡因复合右美托咪定椎旁神经阻滞是一种有效的镇痛技术,可以提供更好的镇痛效果,起效更快,同时具有良好的安全性.
Abstract
Objective To analyze the application effect of ropivacaine combined with dexmedetomidine paravertebral nerve block in lung cancer resection.Methods A total of 96 patients undergoing lung cancer resection in Shishi Hospi-tal from January 2022 to December 2023 were conveniently selected as the research objects.According to different an-esthesia methods,they were divided into compound group,ropivacaine group and general anesthesia group,with 32 cases in each group.The compound group was given ropivacaine combined with dexmedetomidine paravertebral nerve block,the ropivacaine group was given ropivacaine paravertebral nerve block,and the general anesthesia group was given general anesthesia.The hemodynamics,anesthesia quality,adverse reactions and pain degree of the three groups were compared.Results From T1 To T4,the heart rate,mean arterial pressure and oxygen saturation in the compound group were better than those in the ropivacaine group and the general anesthesia group,and the differences were statis-tically significant(all P<0.05).The onset time of sensory block,extubation time,spontaneous breathing recovery time,block maintenance time,remifentanil dosage and sufentanil dosage in the compound group were better than those in the ropivacaine group and the general anesthesia group,and the differences were statistically significant(all P<0.05).The total incidence of adverse reactions in the compound group was 9.38%(3/32),which was lower than 25.00%(8/32)in the ropivacaine group and 31.25%(10/32)in the general anesthesia group,there was no significant difference in the total incidence of adverse reactions among patients in three groups(P>0.05).At 2 h,6 h,12 h and 24 h after opera-tion,the pain scores of the compound group were lower than those of the ropivacaine group and the general anesthesia group,and the differences were statistically significant(all P<0.05).Conclusion Ropivacaine combined with dexme-detomidine paravertebral nerve block is an effective analgesic technique,which can provide better analgesic effect,faster onset,and good safety.
关键词
罗哌卡因/右美托咪定/椎旁神经阻滞/肺癌切除手术Key words
Ropivacaine/Dexmedetomidine/Paravertebral nerve block/Lung cancer resection引用本文复制引用
出版年
2024
NETL
NSTL
万方数据