Application of Ropivacaine Combined with Dexmedetomidine Paraverte-bral Nerve Block in Lung Cancer Resection Surgery
Objective To analyze the application effect of ropivacaine combined with dexmedetomidine paravertebral nerve block in lung cancer resection.Methods A total of 96 patients undergoing lung cancer resection in Shishi Hospi-tal from January 2022 to December 2023 were conveniently selected as the research objects.According to different an-esthesia methods,they were divided into compound group,ropivacaine group and general anesthesia group,with 32 cases in each group.The compound group was given ropivacaine combined with dexmedetomidine paravertebral nerve block,the ropivacaine group was given ropivacaine paravertebral nerve block,and the general anesthesia group was given general anesthesia.The hemodynamics,anesthesia quality,adverse reactions and pain degree of the three groups were compared.Results From T1 To T4,the heart rate,mean arterial pressure and oxygen saturation in the compound group were better than those in the ropivacaine group and the general anesthesia group,and the differences were statis-tically significant(all P<0.05).The onset time of sensory block,extubation time,spontaneous breathing recovery time,block maintenance time,remifentanil dosage and sufentanil dosage in the compound group were better than those in the ropivacaine group and the general anesthesia group,and the differences were statistically significant(all P<0.05).The total incidence of adverse reactions in the compound group was 9.38%(3/32),which was lower than 25.00%(8/32)in the ropivacaine group and 31.25%(10/32)in the general anesthesia group,there was no significant difference in the total incidence of adverse reactions among patients in three groups(P>0.05).At 2 h,6 h,12 h and 24 h after opera-tion,the pain scores of the compound group were lower than those of the ropivacaine group and the general anesthesia group,and the differences were statistically significant(all P<0.05).Conclusion Ropivacaine combined with dexme-detomidine paravertebral nerve block is an effective analgesic technique,which can provide better analgesic effect,faster onset,and good safety.
RopivacaineDexmedetomidineParavertebral nerve blockLung cancer resection
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