Clinical Efficacy of Carbon Dioxide Dot Laser Combined with Platelet-Rich Plasma Treatment of Atrophic Acne Scars
Objective To analyze the effect of carbon dioxide dot laser combined with platelet rich plasma in the treat-ment of atrophic acne scar.Methods A total of 130 patients with atrophic acne scar admitted to Quanzhou Dermatol-ogy Prevention and Treatment Hospital from July 2022 to March 2024 were randomly selected as the study subjects and divided into two groups with 65 cases each according to different treatment regimens.The control group was treated with carbon dioxide dot matrix laser,and the study group was treated with platelet-rich plasma.Clinical effi-cacy,Scar status[Vancouver Scar Scale(VSS)],incidence of adverse events(edema,erythema,pruritus,pigmentation),clinical symptoms(skin flushing,skin erythema,papular pustules,telangiectasia)score were compared and observed.Results The clinical effect of the study group was better than that of the control group,the difference was statistically significant(P<0.05).After treatment,the scar color score of the study group was(1.18±0.28)points,the thickness score was(1.24±0.13)points,the vascular distribution score was(1.07±0.86)points,and the flexibility score was(1.23±0.37)points,they were all lower than(1.69±0.31)points,(1.67±0.36)points,(1.56±0.97)points and(1.85±0.46)points in the control group,and the differences were statistically significant(t=9.843,9.057,3.047,8.467,all P<0.05).There was no significant difference in the total incidence of adverse events between the two groups(P>0.05).Before treatment,there was no significant difference in clinical symptom scores between the two groups(P>0.05);after treat-ment,the clinical symptom score of the study group was lower than that of the control group,and the difference was statistically significant(P<0.05).Conclusion The treatment of patients with atrophic acne scar with carbon dioxide dot matrix laser combined with platelet-rich plasma has high efficacy and safety,and can promote the relief of clinical symptoms.
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