严重肝脏创伤患者行损伤控制剖腹术治疗的临床效果及预后分析
Clinical Effect and Prognosis Analysis of Damage Control Laparotomy in Patients with Severe Liver Trauma
贺东阳1
作者信息
- 1. 福建省福州市福清融强医院普通外科,福建 福州 350300
- 折叠
摘要
目的 探讨严重肝脏创伤患者行损伤控制剖腹术治疗的临床效果及预后.方法 随机选取2021年9月—2023年9月福建省福州市福清融强医院收治的60例严重肝脏创伤患者作为研究对象,根据不同治疗方法分组为对照组与观察组,各30例.对照组行常规开腹手术治疗,观察组行损伤控制剖腹术治疗,比较两组治疗效果、炎性因子水平、并发症发生情况及病死率.结果 两组治疗总有效率、并发症总发生率对比,差异无统计学意义(P均>0.05).治疗后,观察组的C反应蛋白、肿瘤坏死因子-α与白细胞介素-6水平低于对照组,差异有统计学意义(P均<0.05).观察组病死率为0(0/30),低于对照组的20.00%(6/30),差异有统计学意义(χ2=4.630,P<0.05).结论 严重肝脏创伤患者行损伤控制剖腹术治疗的临床效果确切,可减轻患者术后炎性反应,改善疾病预后.
Abstract
Objective To investigate the clinical effect and prognosis of damage control laparotomy in patients with se-vere liver trauma.Methods A total of 60 patients with severe liver trauma admitted to Fuqing Rongqiang Hospital in Fuqing of Fujian Province from September 2021 to September 2023 were randomly selected as the research objects.According to different treatment methods,they were divided into control group and observation group,with 30 cases in each group.The control group was treated with routine laparotomy,and the observation group was treated with damage control laparotomy.The treatment effect,inflammatory factor level,complications and fatality rate were compared be-tween the two groups.Results There was no significant difference in the total effective rate and total complication rate between the two groups(P>0.05).After treatment,the levels of C-reactive protein,tumor necrosis factor-α and inter-leukin-6 in the observation group were lower than those in the control group,and the differences were statistically sig-nificant(all P<0.05).The fatality rate of the observation group was 0(0/30),which was lower than 20.00%(6/30)of the control group,and the difference was statistically significant(χ2=4.630,P<0.05).Conclusion The clinical effect of damage control laparotomy in patients with severe liver trauma is definite,which can reduce the postoperative inflam-matory response and improve the prognosis of the disease.
关键词
严重肝脏创伤/损伤控制剖腹术/炎性反应/预后Key words
Severe liver trauma/Damage control laparotomy/Inflammatory response/Prognosis引用本文复制引用
出版年
2024
NETL
NSTL
万方数据