首页|损伤控制性手术与一期确定性手术治疗严重创伤性肝破裂的临床效果分析

损伤控制性手术与一期确定性手术治疗严重创伤性肝破裂的临床效果分析

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目的 研讨损伤控制性手术与一期确定性手术治疗严重创伤性肝破裂(severe traumatic liver rupture,STLR)的临床价值.方法 随机选取2020年1月—2024年1月经莆田盛兴医院确诊为STLR的患者80例为研究对象,依据不同手术处理方法分为两组,每组40例,对照组行一期确定性手术处理,观察组行损伤控制性手术处理,比较两组患者手术基础指标、不同手术阶段的血清应激因子水平以及术后并发症发生情况.结果 观察组各项手术基础指标(手术时间、术中出血量、体温复常时间、乳酸清除时间及住院时间)均优于对照组,差异有统计学意义(P均<0.05).术后7 d,观察组各项血清应激因子(肾上腺素、皮质醇、C反应蛋白、白细胞介素-6)水平均低于对照组,差异有统计学意义(P均<0.05).观察组并发症总发生率为5.00%(2/40)低于对照组的20.00%(8/40),差异有统计学意义(χ2=4.114,P=0.043).结论 与一期确定性手术相比,损伤控制性手术用于STLR患者,手术时间更短、出血量更少、恢复更快,且可更有效减轻机体应激反应,减少并发症的发生.
Clinical Effect Damage Control Surgery and One-stage Deterministic Sur-gery in the Treatment of Severe Traumatic Liver Rupture
Objective To investigate the clinical value of damage control surgery and one-stage deterministic surgery in the treatment of severe traumatic liver rupture(STLR).Methods A total of 80 patients diagnosed with STLR in Pu-tian Shengxing Hospital from January 2020 to January 2024 were randomly selected as the study objects,and were di-vided into two groups according to different surgical treatment methods,with 40 cases in each group.The control group received one-stage deterministic surgical treatment,and the observation group received damage control surgical treatment.The basic indexes of operation,the levels of serum stress factors at different operation stages and the occur-rence of postoperative complications were compared between the two groups.Results The basic indexes of the observa-tion group(operation time,intraoperative blood loss,temperature normalization time,lactic acid clearance time and length of hospital stay)were better than those of the control group,and the differences were statistically significant(all P<0.05).7 days after surgery,the levels of serum stress factors(epinephrine,cortisol,C-reactive protein,inter-leukin-6)in the observation group were lower than those in the control group,and the differences were statistically significant(all P<0.05).The total complication rate in the observation group was 5.00%(2/40)lower than that in the control group 20.00%(8/40),and the difference was statistically significant(χ2=4.114,P=0.043).Conclusion Com-pared with one-staye deterministic surgery,damage control surgery for STLR patients has shorter operation time,less blood loss,faster recovery,and can more effectively reduce the body's stress response and reduce the occurrence of complications.

Severe traumatic liver ruptureDamage control surgeryOne-stage deterministic surgeryStress factorComplication

李文、林丽青、柯东东

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莆田盛兴医院外科,福建 莆田 351146

莆田九十五医院外科,福建 莆田 351146

莆田学院附属医院外科,福建 莆田 351146

严重创伤性肝破裂 损伤控制性手术 一期确定性手术 应激因子 并发症

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(32)