首页|布拉氏酵母菌对急性感染性腹泻患者症状改善及机体炎症指标的影响分析

布拉氏酵母菌对急性感染性腹泻患者症状改善及机体炎症指标的影响分析

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目的 研讨布拉氏酵母菌对急性感染性腹泻患者症状改善及机体炎症指标的影响.方法 单纯随机选取2022年2月—2024年2月经宁德人民医院确诊为急性感染性腹泻的患者120例作为研究对象,依据不同治疗方法分为对照组和观察组,各60例.对照组接受常规对症处理,观察组基于对照组接受布拉氏酵母菌治疗,比较两组的用药疗效、症状改善状况、机体炎症指标以及用药安全性.结果 观察组临床用药总有效率为95.00%(57/60),高于对照组的83.33%(50/60),差异有统计学意义(χ2=4.227,P=0.039).观察组症状(发热、腹泻、腹痛及呕吐)恢复正常时间短于对照组,差异均有统计学意义(P均<0.05).治疗5 d后,观察组炎症指标水平低于对照组,差异有统计学意义(P<0.05).两组不良反应发生率对比,差异无统计学意义(P>0.05).结论 布拉氏酵母菌用于急性感染性腹泻患者的治疗效果较好,能够促进患者症状改善、减轻机体炎症反应,且用药安全可靠.
To Analyze the Effect of Saccharomyces Boulardii on Symptom Improve-ment and Inflammatory Indexes in Patients with Acute Infectious Diarrhea
Objective To study the effect of Saccharomyces boulardii on the improvement of symptoms and inflamma-tory indexes in patients with acute infectious diarrhea.Methods From February 2022 to February 2024,120 patients with acute infectious diarrhea diagnosed in Ningde People's Hospital were simple randomly selected as the research objects.According to different treatment methods,they were divided into control group and observation group,60 cases in each group.The control group received routine symptomatic treatment,and the observation group received saccharomyces boulardii treatment based on the treatment conditions of the control group.The efficacy,symptom im-provement,body inflammation index and medication safety of the two groups were compared.Results The total effec-tive rate of clinical medication in the observation group was 95.00%(57/60),which was higher than 83.33%(50/60)in the control group,and the difference was statistically significant(χ2=4.227,P=0.039).The time of symptoms returned to normal(fever,diarrhea,abdominal pain and vomiting)in the observation group were shorter than those in the con-trol group,and the differences were statistically significant(all P<0.05).After 5 days of treatment,the levels of inflam-matory index in the observation group was lower than that in the control group,and the difference was statistically sig-nificant(P<0.05).There was no significant difference in the incidence of adverse reactions between the two groups(P>0.05).Conclusion Saccharomyces boulardii has a good therapeutic effect on patients with acute infectious diarrhea,which can promote the improvement of patients'symptoms,reduce the body's inflammatory response,and is safe and reliable.

Acute infectious diarrheaSaccharomyces boulardiiSymptom improvementBody inflammation index

徐叶光、张虹、余云磊、何顺勇

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福建省宁德市宁德人民医院内五科,福建 宁德 352100

福建中医药大学附属人民医院消化科,福建 福州 350004

急性感染性腹泻 布拉氏酵母菌 症状改善 机体炎症指标

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(33)