首页|西甲硅油与奥美拉唑联合疗法在儿童功能性消化不良中的应用效果分析

西甲硅油与奥美拉唑联合疗法在儿童功能性消化不良中的应用效果分析

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目的 评价西甲硅油与奥美拉唑联合治疗儿童功能性消化不良的临床效果.方法 回顾性选取2022年1月—2023年12月龙岩人民医院收治的60例功能性消化不良患儿的临床资料,以不同治疗方法分为联合组和单一组,每组30例,单一组采用奥美拉唑治疗,联合组联合西甲硅油治疗.对比两组不适症状积分、胃功能指标、治疗有效率和不良反应发生率.结果 治疗后,联合组的不适症状积分低于单一组,差异有统计学意义(P<0.05).联合组的胃功能指标优于单一组,差异有统计学意义(P<0.05).联合组治疗有效率为93.33%(28/30),显著高于单一组的73.33%(22/30),差异有统计学意义(χ2=4.320,P<0.05).联合组的不良反应总发生率高于单一组,但两组比较,差异无统计学意义(P>0.05).结论 西甲硅油联合奥美拉唑疗法在治疗儿童功能性消化不良方面表现出明显的治疗效果,对缓解患儿的症状及提升其胃功能具有积极作用,同时不良反应发生率未增加,可考虑作为一种有效的治疗方法,用于儿童功能性消化不良的治疗.
Analysis of the Application Effect of Combined Therapy of Simethicone and Omeprazole in Children with Functional Dyspepsia
Objective To evaluate the clinical effect of simethicone combined with omeprazole in the treatment of functional dyspepsia in children.Methods The clinical data of 60 children with functional dyspepsia admitted to Long-yan People's Hospital from January 2022 to December 2023 were retrospectively selected.They were divided into combined group and single group according to different treatment methods,30 cases in each group.The single group was treated with omeprazole,and the combined group was treated combined with simethicone.The scores of discom-fort symptoms,gastric function index,treatment efficiency and incidence of adverse reactions were compared between the two groups.Results After treatment,the discomfort symptom score of the combined group was significantly lower than that of the single group,and the difference was statistically significant(P<0.05).The gastric function of the com-bined group was better than that of the single group,and the difference was statistically significant(P<0.05).The effec-tive rate of treatment in the combined group was 93.33%(28/30),which was significantly higher than 73.33%(22/30)in the single group,and the difference was statistically significant(χ2=4.320,P<0.05).The total incidence of adverse reactions in the combined group was higher than that in the single group,but there was no statistical significance be-tween the two groups(P>0.05).Conclusion Simethicone therapy combined with omeprazole shows obvious therapeutic effect in the treatment of functional dyspepsia in children.It has a positive effect on relieving the symptoms of chil-dren and improving their gastric function.At the same time,the incidence of adverse reactions has not increased sig-nificantly.It can be considered as an effective treatment method for the treatment of functional dyspepsia in children.

SimethiconeOmeprazoleCombination therapyChildrenFunctional dyspepsiaTherapeutic efficacy evaluation

张婷婷、廖爱萍、王飞飞

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龙岩人民医院儿科,福建 龙岩 364000

青岛市妇女儿童医院儿童消化科,山东 青岛 266000

西甲硅油 奥美拉唑 联合疗法 儿童 功能性消化不良 疗效评估

2024

中外医疗
卫生部医院管理研究所 二十一世纪联合创新医药科学研究院

中外医疗

影响因子:0.909
ISSN:1674-0742
年,卷(期):2024.43(34)