Clinical Efficacy Evaluation of Gastrointestinal Endoscopic Submucosal Dissection In Early Esophageal Cancer Patients
Objective To investigate the efficacy of gastrointestinal endoscopic submucosal dissection in the treatment of early esophageal cancer.Methods A total of 100 patients with early esophageal cancer admitted to Fujian Fuqing City Hospital from March 2021 to March 2024 were randomly selected as the research objects.According to different surgical methods,they were divided into study group and control group,with 50 cases in each group.The control group was treated with endoscopic mucosal resection,and the study group was treated with gastrointestinal endoscopic submucosal dissection.The levels of tumor markers,clinical related indicators and complications were compared be-tween the two groups.Results After operation,the levels of carcinoembryonic antigen,vascular endothelial growth fac-tor,carbohydrate antigen 19-9 and dopamine decarboxylase in the two groups were lower than those before operation,and those in the study group were lower than the control group,the differences were statistically significant(all P<0.05).The operation time(0.36±0.07)h,bleeding volume(86.29±8.32)mL,hospitalization time(4.49±1.22)d,strip-ping area(10.50±2.07)cm2,and resection rate per unit time(18.70±3.26)mm2/min in the study group were better than those in the control group(1.49±0.22)h,(121.29±14.16)mL,(9.01±2.24)d,(7.59±1.21)cm2,(12.22±2.10)mm2/min,the differences were statistically significant(t=34.610,15.069,12.530,8.582,11.816;all P<0.05).The total incidence of complications in the study group was lower than that in the control group,the difference was statistically significant(P<0.05).Conclusion The application of digestive endoscopic submucosal dissection has a significant effect on reduc-ing the incidence of complications in patients with early esophageal cancer.It has outstanding advantages in reducing the area of dissection and reducing the level of postoperative tumor markers.
Early esophageal cancerGastrointestinal endoscopic submucosal dissectionTumor markers
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