环境化学2024,Vol.43Issue(1) :1-13.DOI:10.7524/j.issn.0254-6108.2023021407

耐药菌的环境分布、传播及新型抗菌技术研究进展

A review on environmental distribution,spread,and anti-bacterial technology of antibiotic-resistant bacteria

欧阳富成 曹慧明 陈博磊 李准洁 李智 梁勇
环境化学2024,Vol.43Issue(1) :1-13.DOI:10.7524/j.issn.0254-6108.2023021407

耐药菌的环境分布、传播及新型抗菌技术研究进展

A review on environmental distribution,spread,and anti-bacterial technology of antibiotic-resistant bacteria

欧阳富成 1曹慧明 2陈博磊 2李准洁 2李智 3梁勇2
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作者信息

  • 1. 南方医科大学第一临床医学院,广州,510515;中部战区总医院骨科,武汉,430070
  • 2. 持久性有毒污染物环境与健康危害湖北省重点实验室,环境与健康学院,江汉大学,武汉,430056
  • 3. 中部战区总医院骨科,武汉,430070
  • 折叠

摘要

抗生素的广泛使用导致细菌耐药性增加、多重耐药菌菌群数量急剧增多,严重威胁着人类生命健康.环境中耐药菌(ARB)及耐药基因(ARGs)的存在给临床治疗耐药菌感染带来了巨大挑战.有关医院中常见耐药致病菌的研究已有很多,尚缺乏环境中耐药菌的分布、传播及新型耐药菌抗菌技术等的相关研究.本文综述了耐药菌的环境分布特征及其传播机制,概述了新型抗菌技术及其应用,最后展望了有关环境耐药菌研究的未来发展方向.

Abstract

The widespread use of antibiotics results in the increase of antibiotic-resistant bacteria(ARB)and their potential for drug resistant,which poses a serious threat to human health.The occurrence of ARB and antibiotic resistance genes(ARGs)in the environment presents a great challenge to the clinical treatment of antibiotic resistant bacteria infections.While great efforts have been made to study common drug-resistant pathogens in hospitals,there is still a lack of understanding regarding the distribution and spread of ARB in the environment.Furthermore,the development of new anti-bacterial technology is slow.This paper reviews the environmental distribution characteristics and spread mechanisms of ARB,summarizes the new anti-bacterial technology and its applications,and finally provides prospects for future research on ARB in the environment.

关键词

耐药菌/环境分布/传播/抗菌技术/展望

Key words

antibiotic-resistant bacteria(ARB)/environmental distribution/spread/anti-bacterial technology/prospect

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基金项目

国家自然科学基金(22193051)

军队后勤科研计划项目资助()

出版年

2024
环境化学
中国科学院生态环境研究中心

环境化学

CSTPCD北大核心
影响因子:1.049
ISSN:0254-6108
参考文献量9
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