Recent advances in nontarget discovery of emerging pollutants in the environment
Chemicals from industrial,agricultural,and domestic activities are constantly entering the environment due to anthropogenic influences.In addition,various biotic and abiotic transformations of chemicals further lead to the presence of a wide variety of pollutants and complex transformation products in the environment.A comprehensive understanding of contaminants in samples is a prerequisite for environmental health risk assessment.However,the large number of unknown structures,complex environmental matrices,and low environmental concentrations pose challenges to the clarification of pollutant exposure.A technology with high sensitivity for the identification of unknown contaminants is thus urgently needed.As an emerging analytical strategy,nontarget analysis(NTA)enables the identification of organic compounds in complex matrices where compound information is unknown.NTA will help to reveal pollutants in environmental samples to the greatest extent and provide the critical foundation for risk assessment.In this paper,we review the applications of NTA technology in the identification of emerging pollutants,discuss the advantages,disadvantages,and scope of application of different methods that have been used from three aspects including sample pretreatment,data acquisition,and data processing,and propose challenges and future directions for the development of NTA.
nontarget analysishigh-resolution mass spectrometryenvironmental analysisemerging pollutants
NETL
NSTL
万方数据
