Lung cancer risk assessment of the exposure to atmospheric polycyclic aromatic hydrocarbons based on population attributable fraction and incremental lifetime cancer risk models:A case study in Hefei
The cancer risk caused by exposure to atmospheric organic pollutants in cities has raised increasing global concern.However,the spatial characteristics of the cancer risk in cities remain largely unknown because there are large differences in the distribution of pollution source and population density.In this study,we analyzed the 16 U.S.EPA priority polycyclic aromatic hydrocarbons(PAHs)in the atmosphere in Hefei,the capital city of Anhui province,over one year period.We also estimated the lung cancer risk caused by exposure to atmospheric PAHs based on the population attributable fraction(PAF)and incremental lifetime cancer risk(ILCR)models.Results indicated that the average excess inhalation risk were 9.47 cancer cases per million people.The overall PAF value was 0.78‰,coinciding well with the ILCR value.The cancer risk at urban sites were noticeably higher than those at tourist area site and rural site.The cancer risk was higher in winter and autumn than those in summer and spring.Adults had higher risk of lung cancer than children and adolescents.
polycyclic aromatic hydrocarbons(PAHs)exposure lung cancer riskpopulation attributable fraction(PAF)incremental lifetime cancer risk(ILCR)
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