得克隆类物质检测技术及其研究进展
Research progress on detection methods of Dechloranes
李原琨 1马继平 1黄超囡 1程嘉雯1
作者信息
- 1. 青岛理工大学环境与市政工程学院,青岛,266525
- 折叠
摘要
得克隆类物质(dechloranes)作为一类添加型氯代阻燃剂,广泛应用于电子设备、纺织品等材料的加工生产中.随着该类阻燃剂在生产生活中的大量使用,导致其在环境中存在并不断累积,经多种介质进入人体,进而产生神经毒性,损坏肌肉细胞,对DNA产生破坏作用.得克隆类物质具有持久性、长距离迁移性和生物蓄积性,对人体健康和环境造成严重危害,2018年被欧洲化学品管理署列入第18批高关注化合物清单.美国国家环境保护局将得克隆划归为高产量化学品,中国也将其列入2023年重点管控新污染物清单.因此,环境样品中得克隆类物质污染水平的准确分析和严格控制是至关重要的.由于得克隆类物质在环境中痕量残留,且实际样品存在复杂基质干扰,需将样品前处理技术与检测方法结合以提高分析灵敏度与准确性.本文重点围绕环境样品中得克隆类物质的样品前处理技术及仪器分析方法两方面进行综述,总结了不同样品中得克隆类物质的前处理技术(液液萃取、固相萃取、索氏提取、加速溶剂萃取、基质分散固相萃取等),详细介绍了气相色谱-质谱法、气相色谱-串联质谱法、液相色谱-串联质谱法等检测方法在得克隆类物质检测中的应用.最后,对未来相关分析方法的发展趋势进行了展望.
Abstract
Dechloranes,which are additive-type chlorine flame retardants,are widely used in the process of industrial production,such as electronic equipments and textiles.Due to extensive use and massive emissions in production and daily life,dechloranes enter the human individuals through various medium,leading to neurobehavioral toxicity,muscle injuries,and DNA damage.Dechloranes can pose a significant risk to human health and environment because of the persistent,long-distance transport and bioaccumulation.In 2018,European Chemicals Agency has added dechlorane plus of very high concern to the Candidate List.It is also subject to the United States Environmental Protection Agency's High Production Volume challenge and in the list of Chinese New Pollutants under Key Control.It has become a great challenge to analyze dechloranes in biology and the environment because of the low level and complex matrix interference,hence,a combination of sample pretreatment methods and determination technology is imperative for enhancing the sensitivity and accuracy of analysis.In this paper,various methods for sample pretreatment and instrumental analysis of dechloranes in the environment are reviewed.Sample pretreatment techniques of dechloranes are summarized,such as liquid-liquid extraction(LLE),solid phase extraction(SPE),soxhlet extraction(SE),accelerated solvent extraction(ASE)and matrix solid phase dispersive extraction(MSPD).The applications of instrument methods for dechloranes are discussed in detail,including gas chromatography-mass spectrometry(GC-MS),gas chromatography-tandem mass spectrometry(GC-MS/MS)and liquid chromatography-tandem mass spectrometry(LC-MS/MS).Finally,the future development trends of the relevant analytical methods of dechloranes were proposed.
关键词
得克隆/氯代阻燃剂/样品前处理/检测方法Key words
dechloranes/chlorine flame retardants/pretreatment/determination引用本文复制引用
基金项目
国家自然科学基金(21976099)
国家自然科学基金(22006086)
山东省自然科学基金(ZR2019MB046)
出版年
2024
NETL
NSTL
万方数据