20 kinds of ultra-trace antibiotic residues in medical wastewater were determined by solid phase extraction-high performance liquid chromatography-triple quadrupole mass spectrometry.By optimizing the exper-imental conditions,the method had good linearity in the range of 1.00 µg/L～100 µg/L.The method detection limits were from 0.24 ng/L to 1.22 ng/L.The recoveries of spiked blank and actual samples with three mass concentration levels were 80.2％～108％and 75.8％～114％,respectively,and the RSDs of six measure-ments were 2.4％～8.4％and 1.7％～8.1％,respectively.This method was used to determine ultra-trace antibi-otic residues in the medical wastewater from two Three-A hospitals in Chongqing,the results showed that 11 anti-biotics were detected and the rest were not detected.
关键词
抗生素/固相萃取/高效液相色谱-串联质谱法/医疗废水
Key words
Antibiotics/Solid phase extraction/High performance liquid chromatography-tandem mass spectrometry/Medical wastewater
维普
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