首页|水生动物肠道微生物与环境污染物互作机制的研究进展

水生动物肠道微生物与环境污染物互作机制的研究进展

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环境污染物暴露所导致的水生动物肠道微生物失调已成为当前水生生态环境领域的研究热点,肠道微生物也同时具有代谢环境污染物并改变其毒性的能力.本研究综述了水生动物肠道微生物的群落结构功能及其与宿主健康的关系,分析了环境污染物暴露通过引起肠道微生物失调从而诱导宿主代谢、内分泌、免疫和神经毒性的相关研究结论.环境污染物能通过改变肠道微生物的组成结构、降低肠道微生物的多样性来扰乱肠道微生态稳态,从而导致肠道炎症、胃肠道和神经系统疾病以及肥胖等代谢疾病.此外,本研究还讨论了水生生物肠道微生物对环境污染物的代谢转化过程及其生物可利用性和毒性的影响.本研究全面梳理了环境污染物与水生动物肠道微生物的双向作用,以期为污染物生态效应评估与水生态风险评价提供理论参考.
Review on the interaction between gut microbiota of aquatic animals and environmental pollutants
The imbalance of gut microbiota in aquatic animals caused by environmental pollutants has currently become a research hotspot in the field of aquatic environment.Gut microbes have the potential to transform environmental pollutants and then change their toxicity.This study reviewed the community structure and function of gut microbes in aquatic animals and their relationship with host health.It also analyzed relevant research conclusions on the induction of host metabolism,endocrine,immune and neurotoxicity by environmental pollutant exposure through intestinal microbial imbalance.The research showed that environmental pollutants disrupt gut microbial homeostasis by altering gut microbial composition and reducing gut microbial diversity,leading to intestinal inflammation,gastrointestinal and neurological diseases,and metabolic disorders such as obesity.This study also discussed the metabolic transformation process of environmental pollutants in gut microorganisms and its impact on their bioavailability and toxicity and presented a thorough examination of the bidirectional interaction mechanism between environmental pollutants and gut microorganisms in aquatic animals,with an aim to provide theoretical references for ecological effect assessment and aquatic ecological risks of pollutants.

Environmental pollutantsgut microbiotatoxicitybiotransformationhost

张思琪、侯瑞、徐向荣

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中国科学院南海海洋研究所 中国科学院热带海洋生物资源与生态重点实验室,广东 广州 510301

中国科学院大学,北京 100049

环境污染物 肠道微生物 毒性 生物转化 宿主

广东省自然科学基金自然资源部海洋生态环境科学与技术重点实验室开放基金

2022A1515011498MEEST-2021-03

2024

环境生态学

环境生态学

CSTPCD
ISSN:
年,卷(期):2024.6(4)
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