LncRNA PVT1在肝癌中的研究进展
Research Progress of LncRNA PVT1 in Liver Cancer
唐晓婷 1彭敦煌 1房太勇1
作者信息
- 1. 福建医科大学附属第二医院消化内科,福建泉州 362400
- 折叠
摘要
肝癌是我国常见的恶性肿瘤之一,死亡率亦很高,给我们国家带来了极大的经济社会负担.近年的研究发现长链非编码RNA(long noncoding RNA,lncRNA)参与了肝癌的细胞增殖、迁移、侵袭、转移等过程.本文对lncRNA浆细胞瘤变异易位基因1(plasmacytoma variant translocation gene 1,PVT1)概述的基础上,重点阐述lncRNA PVT1在肝癌的发生、进展、转移等方面的作用.
Abstract
Liver cancer is one of the common malignant tumors in China,with a high mortality rate,which brings great economic and social burden to our country.Recent studies have found that long non coding RNA(lncRNA)is involved in the proliferation,migration,invasion,and metastasis of liver cancer cells.Based on an overview of lncRNA plasma cell tumor variant translocation gene 1(PVT1),this article focuses on the role of lncRNA PVT1 in the occurrence,progression,and metastasis of liver cancer.
关键词
长链非编码码RNA/浆细胞瘤变异易位基因1/原发性肝癌Key words
Long chain non coding RNA/plasma cell tumor variant translocation gene 1/primary liver cancer引用本文复制引用
基金项目
福建省中青年教师教育科研项目(JAT220104)
出版年
2023