Objective Silent brain infarction is a easily overlooked type of cerebral infarction with high incidence and misdiagnosis rate.There is a lack of studies on the association with carotid artery stiffness in young and middle-aged SBI patients.This study analyzed the carotid ultrasound characteristics of young and middle-aged patients with SBI and further explored its correlation with the occurrence of SBI.Methods The clinical data of 164 young and middle-aged patients with perfect head MR examination were retrospectively analyzed and divided into SBI and non-SBI groups according to the presence of cerebral infarction on MRI.Age,sex,carotid ultrasound findings(carotid stiffness,carotid plaque type),laboratory indicators(high-density fat egg,total cholesterol,triglycerides,low-density lipoprotein)were compared.Multivariate Logistic regression analysis of risk factors was performed using the onset of asymptomatic cerebral infarction(SBI)as the dependent variable and the items with statistically significant differences in the above univariate analysis as the independent variables.Results The carotid artery stiffness was present in 46(50.5％)cases of SBI,including 15(32.6％)with hypoechoic plaques,8(17.4％)with strongly echoic plaques,and 23(50.0％)with mixed echoes.Compared with young and middle-aged SBI patients and non-SBI patients,the proportion of age and carotid stiffness was higher than the non-SBI group,and the difference was significant(P＜0.05).Age promoted the development of SBI in young and middle-aged people(OR=1.08,OR95％CI:0.078-0.0.634,P＜0.05),and carotid arteriosclerosis promoted the occurrence of SBI in young and middle-aged people(OR=2.275,OR95％CI:1.122-4.613,P＜0.05).Conclusions Age and this study found that carotid arteriosclerosis promotes the occurrence of SBI and is a risk factor of young and middle-aged SBI.
silent brain infarctionrisk factorsyoung and middle-agedThe carotid artery hardening
维普
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