航空航天医学杂志2025,Vol.36Issue(1) :4-6.

胃上皮内瘤变内镜活检与内镜粘膜下剥离术后的病理诊断差异分析及影响因素研究

Difference analysis of pathological diagnosis and influencing factors of gastric intraepithelial neoplasia after endoscopic biopsy and endoscopic submucosal dissection

杨俊
航空航天医学杂志2025,Vol.36Issue(1) :4-6.

胃上皮内瘤变内镜活检与内镜粘膜下剥离术后的病理诊断差异分析及影响因素研究

Difference analysis of pathological diagnosis and influencing factors of gastric intraepithelial neoplasia after endoscopic biopsy and endoscopic submucosal dissection

杨俊1
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作者信息

  • 1. 安阳市肿瘤医院内镜中心,河南 安阳 455000
  • 折叠

摘要

目的 分析胃上皮内瘤变内镜活检(Gastric Intraepithelial Neoplasia,GIN)与内镜粘膜下剥离术(Endoscopic Submucosal Dissection,ESD)的病理诊断差异分析及影响因素.方法 选取2022 年12 月至2024 年03 月期间在本院接受治疗的 86 例胃黏膜上皮内瘤变患者作为研究对象.分别对患者进行活检与术后病理诊断,并分析诊断结果一致性.将患者根据诊断结果分为病理一致组和病理升级组.对影响胃上皮内瘤变内镜活检与内镜粘膜下剥离术后病理诊断差异的单因素和多因素进行分析.结果 在86 例患者中,69 例病理诊断前后一致,17 例术后病理诊断升级.单因素分析表明,取材数目、表面充血、表面溃疡是升级的危险因素(P<0.05).多因素分析确认这些因素为病理升级的独立危险因素.结论 内镜活检与ESD术后病理存在差异,术前活检提示低级别上皮内瘤变且存在特定风险因素时,需警惕病理低估的可能性.

Abstract

Objective To analyze the difference in pathologic diagnosis between endoscopic biopsy of gastric intraepithelial neoplasia(GIN)and endoscopic submucosal dissection(ESD)and the factors affecting it.Methods 86 patients with gastric mucosal intraepithelial neoplasia who were treated in our hospital from December 2022 to March 2024 were selected as the study objects.Biopsy and postoperative pathological diagnosis were performed respectively,and the consistency of diagnosis results was analyzed.According to the diagnosis results,the patients were divided into pathological consistency group and pathological upgrade group.The single and multiple factors affecting the difference of pathological diagnosis of gastric intraepithelial neoplasia after endoscopic biopsy and endoscopic submucosal dissection were analyzed.Results Of the 86 patients,69 were consistent in pathological diagnosis and 17 were upgraded after operation.Univariate analysis showed that the number of samples,surface congestion and surface ulcer were the risk factors for upgrading(P<0.05).Multivariate analysis identified these factors as independent risk factors for pathological escalation.Conclusions Endoscopic biopsy and ESD postoperative pathology are not the same things.There may be a pathological underestimate when a preoperative biopsy reveals Low-grade Intraepithelial AMI combined with HF.

关键词

胃黏膜上皮内瘤变/内镜下粘膜剥离术/病理活检/诊断差异/影响因素

Key words

Gastric mucosal intraepithelial neoplasia/Endoscopic mucosal dissection/Pathologi-cal biopsy/Difference in diagnosis/Influencing factor

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出版年

2025
航空航天医学杂志
中航工业哈尔滨二四二医院

航空航天医学杂志

影响因子:0.69
ISSN:2095-1434
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