With the continuous improvement of missile speed and guidance accuracy,the mechanical condition of the seeker system is increasingly harsh.In this paper,the crucial main load framework of the seek system was in-vestigated.Based on the theory of structure dynamics,the dynamic model was presented.Then a simulation numer-ical model was established to study its dynamic response characteristics.ANSYS was utilized to conduct modal anal-ysis,flight vibration analysis and impact response analysis,in which the structure deformation,stress distribution and related laws were given.The results showed that the structure design was reasonable,which had extensive guiding significance for the structure design and optimization for the same type of products.